2,3,5-三氯-4-碘吡啶合成路线 (共 2 条)
反应条件
iodine; lithium diisopropyl amide in tetrahydrofuran; hexane T=-75°C;
参考文献
Bobbio, Carla; Schlosser, Manfred
European Journal of Organic Chemistry, 2001 , # 23 p. 4533 - 4536
反应条件
1.1: 59 percent / lithium 2,2,6,6-tetramethylpiperidine; H2O / tetrahydrofuran; methanol / -100 - -75 °C 2.1: isopropylmagnesium chloride / tetrahydrofuran / 0.75 h / -75 °C 2.2: 76 percent / -75 °C View Scheme
参考文献
Bobbio, Carla; Schlosser, Manfred
European Journal of Organic Chemistry, 2001 , # 23 p. 4533 - 4536