bis(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; BoPhoz; hydrogen in methanol; ethyl acetate P=2327.17 Torr; 3 h;

1: With bis(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; (R)-N-[bis(4-methoxyphenyl)phosphino]-N-methyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine in methanol T=25°C; 0.25 h; 2: benzyl 2-tert-butoxycarbonylamino-3-cyclopropylacrylate With hydrogen in methanol P=1277.21 - 1794.37 Torr; 6 h; Product distribution / selectivity;

T=-78°C; 30 h; Photolysis;

1: 33 percent / sodium acetate / 1.5 h / 110 °C 2: 85 percent / sodium methoxide / toluene / 1 h / 25 °C 3: 4-(dimethylamino)pyridine / toluene / 17 h / 20 °C 4: 52 percent / hydrzine hydrate / methanol; toluene; H2O / 4 h / 3 - 7 °C 5: 94 percent / H2; (R)-N-Me-N-(Ph2P)-1-[(S)-2-(Ph2P)ferrocenyl]ethylamine; bis(1,5-cyclooctadienyl)rhodium trifuoromethanesulfonate / methanol; ethyl acetate / 3 h / 2327.17 Torr View Scheme

1: 4-(dimethylamino)pyridine / toluene / 17 h / 20 °C 2: 52 percent / hydrzine hydrate / methanol; toluene; H2O / 4 h / 3 - 7 °C 3: 94 percent / H2; (R)-N-Me-N-(Ph2P)-1-[(S)-2-(Ph2P)ferrocenyl]ethylamine; bis(1,5-cyclooctadienyl)rhodium trifuoromethanesulfonate / methanol; ethyl acetate / 3 h / 2327.17 Torr View Scheme

1: 85 percent / sodium methoxide / toluene / 1 h / 25 °C 2: 4-(dimethylamino)pyridine / toluene / 17 h / 20 °C 3: 52 percent / hydrzine hydrate / methanol; toluene; H2O / 4 h / 3 - 7 °C 4: 94 percent / H2; (R)-N-Me-N-(Ph2P)-1-[(S)-2-(Ph2P)ferrocenyl]ethylamine; bis(1,5-cyclooctadienyl)rhodium trifuoromethanesulfonate / methanol; ethyl acetate / 3 h / 2327.17 Torr View Scheme

1: 99 percent / methanesulfonic acid / toluene / 2 h 2: 83 percent / H2 / Pd/C / methanol / 3 h / 50 °C / 2068.59 Torr View Scheme