2-[(1,3-二氢-1,3-二氧代-2H-异吲哚-2-基)氧基]-2-甲基丙酸乙酯合成路线 （共 3 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
T=35°C; 72 h;
参考文献
AICURIS GMBH and CO. KG; KLENKE, Burkhard; WIEGAND, Irith; SCHIFFER, Guido; BROETZ-OESTERHELT, Heike; MAITI, Samarendra N.; KHAN, Jehangir; REDDY, Andhe; YANG, Zhixiang; HENA, Mostafa; JIA, Guofeng; LIGONG, Ou; LIANG, Hong; YIP, Judy; GAO, Chuanjun; TAJAMMUL, Sabiha; MOHAMMAD, Rahim; BISWAJEET, Ganguli
Patent: WO2013/110643 A1, 2013 ;
Location in patent: Paragraph 00275-0277 ;
反应条件
triethylamine in acetonitrile
参考文献
Bompart; Giral; Malicorne; Puygrenier
European Journal of Medicinal Chemistry, 1988 , vol. 23, # 5 p. 457 - 464
反应条件
hydrazine hydrate in ethanol
T=40°C; 2 h;
参考文献
AICURIS GMBH and CO. KG; KLENKE, Burkhard; WIEGAND, Irith; SCHIFFER, Guido; BROETZ-OESTERHELT, Heike; MAITI, Samarendra N.; KHAN, Jehangir; REDDY, Andhe; YANG, Zhixiang; HENA, Mostafa; JIA, Guofeng; LIGONG, Ou; LIANG, Hong; YIP, Judy; GAO, Chuanjun; TAJAMMUL, Sabiha; MOHAMMAD, Rahim; BISWAJEET, Ganguli
Patent: WO2013/110643 A1, 2013 ;
Location in patent: Paragraph 00278-00280 ;
