4-(1,3-二氧杂环戊烷-2-基)-苯甲醛合成路线 （共 10 条）
反应条件
sodium tetrahydroborate; water
参考文献
WO2005/92847 A1, ;
Page/Page column 32 ;
反应条件
1: 60 percent / NaBH4; EtOH / 0.5 h / 20 °C 2: 25 percent / CBr4; PPh3 / tetrahydrofuran / 9 h / 0 - 20 °C View Scheme
参考文献
Loim; Kelbyscheva
Russian Chemical Bulletin, 2004 , vol. 53, # 9 p. 2080 - 2085
反应条件
toluene-4-sulfonic acid in toluene
3 h; Reflux;
参考文献
Isaad, Jalal; El Achari, Ahmida
Dyes and Pigments, 2013 , vol. 99, # 3 p. 878 - 886
反应条件
1: 2-(4'-bromophenyl)-1,3-dioxolane With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h;
2: (4-morpholinyl)methanone in tetrahydrofuran; hexane
T=-78°C; 3 h;
3: With water in tetrahydrofuran; diethyl ether; hexane
参考文献
Tanaka, Keigo; Yamamoto, Eiichi; Watanabe, Naoaki
Patent: US2009/82403 A1, 2009 ;
Location in patent: Page/Page column 127 ;
反应条件
1: 1,1-ethylenedioxy-1-(4-chlorophenyl)methane With naphthalene; lithium in tetrahydrofuran
T=-78°C; 1.5 h; Inert atmosphere;
2: N,N-dimethyl-formamide in tetrahydrofuran
2 h; Inert atmosphere;
参考文献
Martinez, Ricardo; Ramon, Diego J.; Yus, Miguel
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 9 p. 1235 - 1240
反应条件
triethylsilane; palladium diacetate; sodium carbonate; 1,4-di(diphenylphosphino)-butane in N,N-dimethyl-formamide
T=85°C; Inert atmosphereSealed tube;
参考文献
Ueda, Tsuyoshi; Konishi, Hideyuki; Manabe, Kei
Angewandte Chemie - International Edition, 2013 , vol. 52, # 33 p. 8611 - 8615
Angew. Chem., 2013 , vol. 125, # 33 p. 8773 - 8777,5
反应条件
1: 78 percent / DEAD, PPh3 / tetrahydrofuran / 1.) room temp., 2 h, 2.) 50 deg C, 16 h
2: tetrahydrofuran / 3 h / Ambient temperature; Irradiation
3: air
View Scheme
参考文献
Blankespoor, Ronald L.; Smart, Robert P.; Batts, Eric D.; Kiste, Alan A.; Lew, Rebecca E.; Vliet, Marc E. Vander
Journal of Organic Chemistry, 1995 , vol. 60, # 21 p. 6852 - 6859
反应条件
1: tetrahydrofuran / 3 h / Ambient temperature; Irradiation
2: air
View Scheme
参考文献
Blankespoor, Ronald L.; Smart, Robert P.; Batts, Eric D.; Kiste, Alan A.; Lew, Rebecca E.; Vliet, Marc E. Vander
Journal of Organic Chemistry, 1995 , vol. 60, # 21 p. 6852 - 6859
反应条件
air
Yield given. Yields of byproduct given;
参考文献
Blankespoor, Ronald L.; Smart, Robert P.; Batts, Eric D.; Kiste, Alan A.; Lew, Rebecca E.; Vliet, Marc E. Vander
Journal of Organic Chemistry, 1995 , vol. 60, # 21 p. 6852 - 6859
反应条件
toluene-4-sulfonic acid in benzene
2 h; Heating;
参考文献
Loim; Kelbyscheva
Russian Chemical Bulletin, 2004 , vol. 53, # 9 p. 2080 - 2085
