(三甲基硅基)乙酸乙酯合成路线 （共 118 条）
反应条件
boron trifluoride diethyl etherate 1.)ethyl trimethylsilylacetate, ether, -78 grad C, warmed to rt., stirred overnight, 2.) BF3OEt2, CH2Cl2, 2 h, rt.; Yield given. Multistep reaction;
参考文献
Larson, Gerald L.; Hernandez, David
Tetrahedron Letters, 1982 , vol. 23, # 10 p. 1035 - 1038
反应条件
tetrabutylammonium fluoride absorbed on silica gel in tetrahydrofuran 8.5 h; Ambient temperature;
参考文献
Gambacorta, Augusto; Turchetta, Stefano; Botta, Maurizio
Synthetic Communications, 1989 , vol. 19, # 13-14 p. 2441 - 2448
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 7 h; Ambient temperature;
参考文献
Nakamura, Eiichi; Hashimoto, Koichi; Kuwajima, Isao
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 3 p. 805 - 808
反应条件
(i) dicyclohexylamine, nBuLi, (ii) /BRN= 605573/; Multistep reaction;
参考文献
Shimoji,K. et al.
Journal of the American Chemical Society, 1974 , vol. 96, # 5 p. 1620 - 1621
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
Journal of the American Chemical Society, , vol. 98, p. 2346 - 2348
反应条件
cesium fluoride in neat (no solvent) 1.5 h; Irradiation;
参考文献
Latouche, R.; Texier-Boullet, F.; Hamelin, J.
Bulletin de la Societe Chimique de France, 1993 , vol. 130, p. 535 - 546
反应条件
1: With Verkade’s superbase in tetrahydrofuran T=20°C; Peterson olefination; 24 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; Peterson olefination; 1 h; Inert atmosphere; stereoselective reaction;
参考文献
Wadhwa, Kuldeep; Verkade, John G.
Journal of Organic Chemistry, 2009 , vol. 74, # 11 p. 4368 - 4371
反应条件
2.) toluene, reflux.; Yield given. Multistep reaction;
参考文献
Coppola, Gary M.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1217 - 1221
反应条件
sulfuric acid 1.)ethyl trimethylsilylacetate, ether, -78 grad C, warmed to rt., stirred overnight, 2.) conc. H2SO4/THF, stirred for 15 h; Yield given. Multistep reaction;
参考文献
Larson, Gerald L.; Hernandez, David
Tetrahedron Letters, 1982 , vol. 23, # 10 p. 1035 - 1038
反应条件
boron trifluoride diethyl etherate 1.)ethyl trimethylsilylacetate, ether, -78 grad C, warmed to rt., stirred overnight, 2.) BF3OEt2, CH2Cl2, 2 h, rt.; Yield given. Multistep reaction;
参考文献
Larson, Gerald L.; Hernandez, David
Tetrahedron Letters, 1982 , vol. 23, # 10 p. 1035 - 1038
