5-[(3aR,6S,6aS)-2,5,5-三氧代-1,3,3a,4,6,6a-六氢噻吩并[3,4-d]咪唑-6-基]戊酸合成路线 （共 3 条）
→
40720-05-65-[(3aR,6S,6aS)-2,5,5-三氧代-1,3,3a,4,6,6a-六氢噻吩并[3,4-d]咪唑-6-基]戊酸
反应条件
dihydrogen peroxide; acetic acid in water
T=20°C; 65 h;
参考文献
Sachon, Emmanuelle; Tasseau, Olivier; Lavielle, Solange; Sagan, Sandrine; Bolbach, Gerard
Analytical Chemistry, 2003 , vol. 75, # 23 p. 6536 - 6543
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40720-05-65-[(3aR,6S,6aS)-2,5,5-三氧代-1,3,3a,4,6,6a-六氢噻吩并[3,4-d]咪唑-6-基]戊酸
反应条件
water; sodium hydroxide in methanol
参考文献
LIFE TECHNOLOGIES CORPORATION; Ying, Lai-Qiang; Branchauo, Bruce; Zhang, Yu-Zhong; Yue, Stephen
Patent: US2014/11255 A1, 2014 ;
Location in patent: Paragraph 0157; 0158 ;
→
40720-05-65-[(3aR,6S,6aS)-2,5,5-三氧代-1,3,3a,4,6,6a-六氢噻吩并[3,4-d]咪唑-6-基]戊酸
反应条件
potassium permanganate; sodium carbonate
参考文献
Koegl; de Man
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1941 , vol. 269, p. 89
