5’-O-(叔丁基二甲基甲硅烷基)胸苷合成路线 （共 23 条）
反应条件
1H-imidazole in N,N-dimethyl-formamide T=20°C; 5 h;
参考文献
D'Onofrio, Jennifer; De Napoli, Lorenzo; Di Fabio, Giovanni; Montesarchio, Daniela
Synlett, 2006 , # 6 p. 845 - 848
反应条件
water; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate in acetonitrile T=75°C; 2.5 h;
参考文献
Ramasamy, Kanda S.; Averett, Devron
Synlett, 1999 , # 6 p. 709 - 712
反应条件
water; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate in acetonitrile T=75°C; 0.25 h;
参考文献
Ramasamy, Kanda S.; Bandaru, Rajanikanth; Averett, Devron
Synthetic Communications, 1999 , vol. 29, # 16 p. 2881 - 2894
反应条件
triethylamine in N,N-dimethyl-formamide T=20°C; Hydrolysis; 1 h;
参考文献
Abbas, Sahar; Hayes, Christopher J.
Tetrahedron Letters, 2000 , vol. 41, # 22 p. 4513 - 4517
反应条件
triethylamine; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide Substitution; coupling;
参考文献
Abbas, Sahar; Hayes, Christopher J.
Tetrahedron Letters, 2000 , vol. 41, # 22 p. 4513 - 4517
反应条件
1H-imidazole in N,N-dimethyl-formamide 2.5 h; Ambient temperature;
参考文献
Buchko; Hruska; Sadana
Canadian Journal of Chemistry, 1989 , vol. 67, # 1 p. 109 - 119
反应条件
1: imidazole / dimethylformamide / 3 h / Ambient temperature 2: 80percent acetic acid / 3 h / Ambient temperature View Scheme
参考文献
Breiner; Rose; Dunn; MacDiarmid; Bardos
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2596 - 2602
反应条件
1: imidazole / dimethylformamide / 3 h / Ambient temperature 2: 80percent acetic acid / 3 h / Ambient temperature View Scheme
参考文献
Breiner; Rose; Dunn; MacDiarmid; Bardos
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2596 - 2602
反应条件
meta-chloroperoxybenzoic acid; phenyl silane in toluene 20 h; Heating;
参考文献
Antonov, K. V.; Karpeiskii, A. M.; Miroshnikov, A. I.
Russian Journal of Bioorganic Chemistry, 1994 , vol. 20, # 4 p. 236 - 240
Bioorganicheskaya Khimiya, 1994 , vol. 20, # 4 p. 433 - 438
反应条件
1: 1.) imidazole, 2.) pyridine / 1.) DMF, 5 h, 2.) reflux, 2 h 2: 80percent acetic acid / 3 h / Ambient temperature View Scheme
参考文献
Breiner; Rose; Dunn; MacDiarmid; Bardos
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2596 - 2602
