4,16-雄二烯-3-酮合成路线 （共 18 条）
反应条件
lithium azide in N,N-dimethyl-formamide T=90°C; Substitution; 9 h;
参考文献
Synthesis, , # 8 p. 1373 - 1385
反应条件
1: 100 percent / pyridine / 0.25 h / 0 - 20 °C 2: 10 percent / 18-crown-6 / benzene / 72 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 34 p. 6145 - 6148
反应条件
1: triethylamine; iodine / 1,4-dioxane / 0.5 h 2: hydrogenchloride / ethanol; water / 2.5 h / |Reflux 3: potassium carbonate; indole; copper(l) iodide; N-methyl-2-(methylamino)ethylamine / dimethyl sulfoxide / 24 h / 100 °C / |Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 34 p. 7823 - 7832
反应条件
1: NH2NH2•xH2O; triethylamine / ethanol / 2 h / |Reflux 2: triethylamine; iodine / 1,4-dioxane / 0.5 h 3: hydrogenchloride / ethanol; water / 2.5 h / |Reflux 4: potassium carbonate; indole; copper(l) iodide; N-methyl-2-(methylamino)ethylamine / dimethyl sulfoxide / 24 h / 100 °C / |Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 34 p. 7823 - 7832
反应条件
18-crown-6 ether in benzene 72 h; Heating;
参考文献
Tetrahedron Letters, , vol. 37, # 34 p. 6145 - 6148
反应条件
1: triethylamine; iodine / 1,4-dioxane / 0.5 h 2: hydrogenchloride / ethanol; water / 2.5 h / |Reflux 3: potassium carbonate; 2,2,6,6-tetramethylheptane-3,5-dione; copper(l) iodide / dimethyl sulfoxide / 24 h / 100 °C / |Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 34 p. 7823 - 7832
反应条件
1: NH2NH2•xH2O; triethylamine / ethanol / 2 h / |Reflux 2: triethylamine; iodine / 1,4-dioxane / 0.5 h 3: hydrogenchloride / ethanol; water / 2.5 h / |Reflux 4: potassium carbonate; 2,2,6,6-tetramethylheptane-3,5-dione; copper(l) iodide / dimethyl sulfoxide / 24 h / 100 °C / |Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 34 p. 7823 - 7832
反应条件
T=300°C; Erhitzen unter Stickstoff;
参考文献
Helvetica Chimica Acta, , vol. 28, p. 618,625
