5-氯-2-硝基苯甲酰胺合成路线 （共 12 条）
反应条件
ammonium hydroxide; diethyl ether
参考文献
Hour; Huang; Kuo; Xia; Bastow; Nakanishi; Hamel; Lee
Journal of Medicinal Chemistry, 2000 , vol. 43, # 23 p. 4479 - 4487
反应条件
ammonium hydroxide; thionyl chloride 1.) PhMe, reflux; Multistep reaction;
参考文献
Hour; Huang; Kuo; Xia; Bastow; Nakanishi; Hamel; Lee
Journal of Medicinal Chemistry, 2000 , vol. 43, # 23 p. 4479 - 4487
参考文献
Montagne
Recueil des Travaux Chimiques des Pays-Bas, 1900 , vol. 19, p. 55
参考文献
Montagne
Recueil des Travaux Chimiques des Pays-Bas, 1900 , vol. 19, p. 55
参考文献
American Home Products Corporation
Patent: US5187168 A1, 1993 ;
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Gita, Haruhisa; Sobe, Yoshiaki; Akaku, Haruo; Ekine, Rena; Oto, Yuso; Isawa, Satoru; Hayashi, Hideya
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 549 - 551
反应条件
thionyl chloride Heating;
参考文献
Lamara; Redhouse; Smalley; Thompson
Tetrahedron, 1994 , vol. 50, # 18 p. 5515 - 5525
反应条件
stannous chloride dihydrate in acetonitrile Reflux;
参考文献
Wang, Man-Man; Dou, Guo-Lan; Shi, Da-Qing
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 4 p. 939 - 943
反应条件
1: SOCl2 / Heating 2: 15 percent TiCl3 / acetone; H2O / 0.5 h View Scheme
参考文献
Lamara; Redhouse; Smalley; Thompson
Tetrahedron, 1994 , vol. 50, # 18 p. 5515 - 5525
反应条件
1: 81 percent / 0.75 h / Heating 2: 76 percent / hydrogen / Pd/C / ethanol / 3 h / 20 °C / 2068.59 Torr View Scheme
参考文献
Hour; Lee; Chen; Zhao
British Journal of Pharmacology, 2013 , vol. 169, # 7 p. 1574 - 1586
