N-[2-(3,4-二甲氧基苯基)乙基]-4-甲氧基苯基乙酰胺合成路线 （共 7 条）
参考文献
YUN-CHOI, HYE-SOOK; CHANG, KI CHURL; LEE, DUCK HYUNG
Patent: WO2003/95426 A1, 2003 ;
Location in patent: Page/Page column 41-42 ;
参考文献
Kuo, Reen-Yen; Wu, Chin-Chung; Chang, Fang-Rong; Yeh, Jwu-Lai; Chen, Ing-Jun; Wu, Yang-Chang
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 821 - 823
反应条件
1: thionyl chloride / CH2Cl2
2: 83 percent / CH2Cl2
View Scheme
参考文献
Kuo, Reen-Yen; Wu, Chin-Chung; Chang, Fang-Rong; Yeh, Jwu-Lai; Chen, Ing-Jun; Wu, Yang-Chang
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 821 - 823
反应条件
triethylamine in dichloromethane
T=20°C; 3 h;
参考文献
Santangelo Freel, Rose M.; Ogden, Kevin K.; Strong, Katie L.; Khatri, Alpa; Chepiga, Kathryn M.; Jensen, Henrik S.; Traynelis, Stephen F.; Liotta, Dennis C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 13 p. 5351 - 5381
反应条件
1: thionyl chloride / dichloromethane / 0.25 h
2: triethylamine / dichloromethane / 3 h / 20 °C
View Scheme
参考文献
Santangelo Freel, Rose M.; Ogden, Kevin K.; Strong, Katie L.; Khatri, Alpa; Chepiga, Kathryn M.; Jensen, Henrik S.; Traynelis, Stephen F.; Liotta, Dennis C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 13 p. 5351 - 5381
反应条件
1: aqueous-alcoholic hydrochloric acid / Electrolysis.bei der elektrolytischen Reduktion an einer Bleikathode
2: NaOH-solution
View Scheme
参考文献
Kondo; Kondo
Journal fuer Praktische Chemie (Leipzig), 1930 , vol. <2>126, p. 46
Full Text Show Details
Kondo; Kondo
Yakugaku Zasshi, 1928 , vol. 48, p. 57
Chem. Zentralbl., 1928 , vol. 99, # II p. 55
反应条件
1: With trichlorophosphate in acetonitrile
0.5 h; Heating / reflux;
2: With sodium tetrahydroborate; ammonia in methanol; water
T=20°C; pH=7 - 8; 0.25 h;
参考文献
Education Center of Traditional Chinese Medicine Co.; Hideo Nakajima
Patent: US2006/30586 A1, 2006 ;
Location in patent: Page/Page column 9 ;
