2,4-二羟基-3-丙基苯乙酮合成路线 （共 26 条）
反应条件
hydrogen; platinum on activated charcoal in tetrahydrofuran; toluene P=1551.4 Torr; Ambient temperature;
参考文献
Manchand; Micheli; Saposnik
Tetrahedron, 1992 , vol. 48, # 43 p. 9391 - 9398
反应条件
in hexane; water; hydrogen bromide; acetic acid; ethyl acetate
参考文献
Eli Lilly and Company
Patent: US4777299 A1, 1988 ;
参考文献
MERCK FROSST CANADA INC.
Patent: EP244164 A1, 1987 ;
反应条件
1: 76 percent / K2CO3, KI / acetone / 24 h / Heating 2: 80 percent / xylene / 18 h / 215 °C 3: 96 percent / H2 / 5 percent Pt/C / toluene; tetrahydrofuran / 1551.4 Torr / Ambient temperature View Scheme
参考文献
Manchand; Micheli; Saposnik
Tetrahedron, 1992 , vol. 48, # 43 p. 9391 - 9398
反应条件
1: 80 percent / xylene / 18 h / 215 °C 2: 96 percent / H2 / 5 percent Pt/C / toluene; tetrahydrofuran / 1551.4 Torr / Ambient temperature View Scheme
参考文献
Manchand; Micheli; Saposnik
Tetrahedron, 1992 , vol. 48, # 43 p. 9391 - 9398
反应条件
aluminium trichloride in dichloromethane
参考文献
Pinkerton, Anthony B.; Cube, Rowena V.; Hutchinson, John H.; Rowe, Blake A.; Schaffhauser, Herve; Zhao, Xiumin; Daggett, Lorrie P.; Vernier, Jean-Michel
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 21 p. 5329 - 5332
反应条件
1: aqueous NaOH 2: ethanol; palladium / Hydrogenation 3: ZnCl2; diethyl ether / und Erwaermen des Reaktionsprodukts mit Wasser View Scheme
参考文献
Baker; Lothian
Journal of the Chemical Society, 1935 , p. 628,631
反应条件
1: ethanol; palladium / Hydrogenation 2: ZnCl2; diethyl ether / und Erwaermen des Reaktionsprodukts mit Wasser View Scheme
参考文献
Baker; Lothian
Journal of the Chemical Society, 1935 , p. 628,631
反应条件
diethyl ether; zinc(II) chloride und Erwaermen des Reaktionsprodukts mit Wasser;
参考文献
Baker; Lothian
Journal of the Chemical Society, 1935 , p. 628,631
反应条件
potassium carbonate in acetone
参考文献
Hoffmann-La Roche Inc.
Patent: US4672066 A1, 1987 ;
US 4672066 A
