1: methyl 2-bromo-2-methyl-propionate With zinc in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphereSealed tube; 2: 2-methoxybromobenzene With [P(t-Bu)3Pd(μ-Br)]2 in tetrahydrofuran T=20°C; 4 h; Inert atmosphereSealed tube;

1: 2-methylpropanoic acid methyl ester With sodium hexamethyldisilazane in toluene T=0°C; 1 h; Inert atmosphereSealed tube; 2: With zinc(II) chloride in tetrahydrofuran; toluene T=70°C; 1 h; Inert atmosphereSealed tube; 3: 2-methoxybromobenzene With [P(t-Bu)3Pd(μ-Br)]2 in tetrahydrofuran; toluene T=70°C; 4 h; Inert atmosphereSealed tube;

lithium diisopropyl amide