4-苯基-4-羟基哌啶合成路线

参考文献

Pryde, David C.; Corless, Martin; Fenwick, David R.; Mason, Helen J.; Stammen, Blanda C.; Stephenson, Peter T.; Ellis, David; Bachelor, David; Gordon, David; Barber, Christopher G.; Wood, Anthony; Middleton, Donald S.; Blakemore, David C.; Parsons, Gemma C.; Eastwood, Rachel; Platts, Michelle Y.; Statham, Keith; Paradowski, Kerry A.; Burt, Catherine; Klute, Wolfgang
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 4 p. 1084 - 1088

40807-61-24-苯基-4-羟基哌啶

10338-69-94-苯基-1,2,3,6-四氢吡啶

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7106 - 7109

40807-61-24-苯基-4-羟基哌啶

参考文献

US6051712 A1, ;
US 6051712 A

40807-61-24-苯基-4-羟基哌啶+

3874-54-24-氯-4'-氟苯丁酮

3109-12-4去氯氟哌醇

参考文献

Janssen et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1959 , vol. 1, p. 281,284

40807-61-24-苯基-4-羟基哌啶+

71-43-2苯

34273-01-34-N-甲基苄基-n-乙氧甲酰哌啶双盐酸盐

参考文献

Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705

40807-61-24-苯基-4-羟基哌啶+

108-90-7氯苯

40421-34-94,4-二(4-氯苯基)哌啶+

34273-01-34-N-甲基苄基-n-乙氧甲酰哌啶双盐酸盐

参考文献

Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705

40807-61-24-苯基-4-羟基哌啶+

24424-99-5二碳酸二叔丁酯

172734-33-74-羟基-4-苯基哌啶-1-羧酸叔丁酯

参考文献

ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC.; ADDEX PHARMA S.A.
Patent: WO2009/33704 A1, 2009 ;
Location in patent: Page/Page column 38 ;
WO 2009/033704 A1

40807-61-24-苯基-4-羟基哌啶+

34619-03-9

172734-33-74-羟基-4-苯基哌啶-1-羧酸叔丁酯

参考文献

Meiji Seika Kaisha, Ltd.
Patent: US6355642 B1, 2002 ;
Location in patent: Page column 30 ;

40807-61-24-苯基-4-羟基哌啶+

501-53-1氯甲酸苄酯

31637-11-3+

3742-91-41-哌啶羧酸苄酯

参考文献

Zeneca Limited
Patent: US5654299 A1, 1997 ;

40807-61-24-苯基-4-羟基哌啶

76691-10-6

参考文献

Pratap, Ram; Gupta, R. C.; Srimal, R. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 8 p. 695 - 698