1-(3-环丙基苯基)乙酮合成路线 （共 2 条）
反应条件
1: 3-(2-methyl-[1,3]dioxolan-2-yl)-1-bromobenzene; cyclopropyl-magnesium bromide With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
5 h; Heating / reflux;
2: cyclopropyl-magnesium bromide in tetrahydrofuran
5 h; Heating / reflux;
3: With hydrogenchloride in tetrahydrofuran; water
T=20°C; 1.5 h;
参考文献
Chu, Xin-Jie; Ding, Qingjie; Jiang, Nan; Kim, Kyungjin; Lovey, Allen John; McComas, Warren William; Mullin JR., John Guilfoyle; Tilley, Jefferson Wright
Patent: US2004/6058 A1, 2004 ;
Location in patent: Page/Page column 29 ;
US 20040006058 A1
反应条件
K3PO4*7H2O; C45H53ClFeNO2PPd in water; toluene
T=100°C; Suzuki coupling; 3 h; Inert atmosphere;
参考文献
Zhang, Min; Cui, Xiuling; Chen, Xiaopei; Wang, Lianhui; Li, Jingya; Wu, Yusheng; Hou, Lifen; Wu, Yangjie
Tetrahedron, 2012 , vol. 68, # 3 p. 900 - 905
