2-甲氧基吡啶-4-戊酰硼酸合成路线 （共 11 条）
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in N,N-dimethyl-formamide T=80°C; 4 h; Inert atmospheremicrowave irradiation;
参考文献
Almirall, S.A.; Eastwood, Paul Robert; Gonzalez Rodriguez, Jacob; Bach Taña, Jordi; Pages Santacana, Lluis Miquel; Taltavull Moll, Joan; Caturla Javaloyes, Juan Francisco
Patent: EP2338888 A1, 2011 ;
Location in patent: Paragraph 0213; 0214 ;
EP 2338888 A1
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in N,N-dimethyl-formamide T=80°C;
参考文献
Fraley, Mark E; Rubino, Robert S; Hoffman, William F; Hambaugh, Scott R; Arrington, Kenneth L; Hungate, Randall W; Bilodeau, Mark T; Tebben, Andrew J; Rutledge, Ruth Z; Kendall, Richard L; McFall, Rosemary C; Huckle, William R; Coll, Kathleen E; Thomas, Kenneth A
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 24 p. 3537 - 3541
反应条件
potassium acetate; PdCl2[dppf] in N,N-dimethyl-formamide
参考文献
DeFeo-Jones, Deborah; Heimbrook, David C.; Jones, Raymond E.
Patent: US2002/41880 A1, 2002 ;
反应条件
C52H67ClFeNPPd; potassium acetate in 1,4-dioxane T=110°C; Suzuki-Miyaura coupling; 6 h; Inert atmosphere;
参考文献
Wang, Lianhui; Li, Jingya; Cui, Xiuling; Wu, Yusheng; Zhu, Zhiwu; Wu, Yangjie
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 11-12 p. 2002 - 2010
反应条件
1: 43 percent / NaNO2; NaBr; CuSO4 / H2SO4 / 0 °C 2: 100 percent / PdCl2(dppf); KOAc / dimethylformamide / 80 °C View Scheme
参考文献
RESEARCH TRIANGLE INSTITUTE; CARROLL, Frank Ivy; ONDACHI, Pauline Wanjiku
Patent: WO2012/24615 A1, 2012 ;
WO 2012/024615 A1
反应条件
1: 48 percent / HNO3; H2SO4 / 100 °C 2: 98 percent / Fe; AcOH / 100 °C 3: 43 percent / NaNO2; NaBr; CuSO4 / H2SO4 / 0 °C 4: 100 percent / PdCl2(dppf); KOAc / dimethylformamide / 80 °C View Scheme
参考文献
RESEARCH TRIANGLE INSTITUTE; CARROLL, Frank Ivy; ONDACHI, Pauline Wanjiku
Patent: WO2012/24615 A1, 2012 ;
WO 2012/024615 A1
反应条件
1: 98 percent / Fe; AcOH / 100 °C 2: 43 percent / NaNO2; NaBr; CuSO4 / H2SO4 / 0 °C 3: 100 percent / PdCl2(dppf); KOAc / dimethylformamide / 80 °C View Scheme
参考文献
RESEARCH TRIANGLE INSTITUTE; CARROLL, Frank Ivy; ONDACHI, Pauline Wanjiku
Patent: WO2012/24615 A1, 2012 ;
WO 2012/024615 A1
反应条件
1: copper(l) iodide / methanol / 160 °C 2: copper(I) bromide; sodium nitrite; hydrogen bromide 3: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 80 °C View Scheme
参考文献
RESEARCH TRIANGLE INSTITUTE; CARROLL, Frank Ivy; ONDACHI, Pauline Wanjiku
Patent: WO2012/24615 A1, 2012 ;
WO 2012/024615 A1
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane 2: nitric acid; sulfuric acid / 100 °C 3: acetic acid; iron / 100 °C 4: copper(I) bromide; sodium nitrite; hydrogen bromide 5: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 80 °C View Scheme
参考文献
RESEARCH TRIANGLE INSTITUTE; CARROLL, Frank Ivy; ONDACHI, Pauline Wanjiku
Patent: WO2012/24615 A1, 2012 ;
WO 2012/024615 A1
反应条件
(iPrPNP)CoCH2SiMe3 in tetrahydrofuran T=80°C; 24 h; Inert atmosphereGlovebox;
参考文献
Obligacion, Jennifer V.; Semproni, Scott P.; Chirik, Paul J.
Journal of the American Chemical Society, 2014 , vol. 136, # 11 p. 4133 - 4136
