1,3-苯并恶唑-2-甲酰氯合成路线 （共 5 条）
反应条件
diethyl ether; phenyl-magnesium bromide
参考文献
Skraup; Moser
Chemische Berichte, 1922 , vol. 55, p. 1097
反应条件
triethylamine 3 h; Reflux;
参考文献
Vodela, Sunil; Mekala, Raghu Vardhan Reddy; Danda, Ravinder Reddy; Kodhati, Venkateshwarlu
Chinese Chemical Letters, 2013 , vol. 24, # 7 p. 625 - 628
反应条件
thionyl chloride in ethanol
T=20°C; 4 h;
参考文献
Vodela, Sunil; Mekala, Raghu Vardhan Reddy; Danda, Ravinder Reddy; Kodhati, Venkateshwarlu
Chinese Chemical Letters, 2013 , vol. 24, # 7 p. 625 - 628
反应条件
1: 2N NaOH / methanol / 2 h / Ambient temperature
2: (COCl)2 / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Romero; Morge; Biles; Berrios-Pena; May; Palmer; Johnson; Smith; Busso; Tan; Voorman; Reusser; Althaus; Downey; So; Resnick; Tarpley; Aristoff
Journal of Medicinal Chemistry, 1994 , vol. 37, # 7 p. 999 - 1014
参考文献
Skraup; Moser
Chemische Berichte, 1922 , vol. 55, p. 1097
