对乙酰氨基-邻甲氧基苯甲酸甲酯合成路线 （共 45 条）
反应条件
1: sodium hydroxide / N,N-dimethyl-formamide
2: N-bromosuccinmide / N,N-dimethyl-formamide
3: sodium hydroxide / ethanol
View Scheme
参考文献
Deng, Xin; Zhao, Xinxin; Han, Jing; Wang, Jingjie; Huang, Wenlong; Qian, Hai; Ge, Liang
Letters in Drug Design and Discovery, 2012 , vol. 9, # 5 p. 489 - 493
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide
2 h; Reflux;
参考文献
Kuroyanagi, Jun-Ichi; Kanai, Kazuo; Sugimoto, Yuuichi; Horiuchi, Takao; Achiwa, Issei; Takeshita, Hiroshi; Kawakami, Katsuhiro
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 21 p. 7593 - 7606
反应条件
1: 78.8 percent / K2CO3 / acetonitrile / 24 h / Heating
2: 96.5 percent / NCS / dimethylformamide / 3 h / 70 °C
View Scheme
参考文献
SUVEN LIFE SCIENCES LIMITED; Nirogi, Ramakrishna; Mohammed, Abdul Rasheed; Yarlagadda, Suresh; Ravella, Srinivasa Rao; Shinde, Anil Karbhari; Kamphampati, Ramasastri; Roayapalley, Praveen Kumar; Jayarajan, Pradeep; Bhyrapuneni, Gopinadh; Patnala, Sriramachandra Murthy; Ravula, Jyothsna; Jasti, Venkateswarlu
Patent: US2014/187581 A1, 2014 ;
反应条件
1: 97 percent / potassium carbonate / acetone / 8 h / Heating
2: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C
3: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature
4: 73 percent / NaOMe / methanol / 2 h / -15 °C
5: 87 percent / xylene / 4 h / Heating
View Scheme
参考文献
MacKenzie, A. Roderick; Moody, Christopher J.; Rees, Charles W.
Tetrahedron, 1986 , vol. 42, # 12 p. 3259 - 3268
反应条件
1: 92 percent / potassium carbonate / acetone / 24 h / Ambient temperature
2: 83 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C
3: 100 percent / BaMnO4 / CHCl3 / 1 h / Heating
View Scheme
参考文献
MacKenzie, A. Roderick; Moody, Christopher J.; Rees, Charles W.
Tetrahedron, 1986 , vol. 42, # 12 p. 3259 - 3268
