H-ARG-ALA-OH合成路线 （共 10 条）
反应条件
morpholine in methanol; N,N-dimethyl-formamide
T=20°C; 1 h;
参考文献
Hellwig, Michael; Geissler, Stefanie; Matthes, Rene; Peto, Anett; Silow, Christoph; Brandsch, Matthias; Henle, Thomas
ChemBioChem, 2011 , vol. 12, # 8 p. 1270 - 1279
反应条件
ammonium formate; palladium on activated charcoal in ethanol
1 h; H2/Pd was tested as well; Product distribution;
参考文献
Kulikov, S. V.; Sokolova, N. Yu.; Samartsev, M. A.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, p. 1625 - 1631
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 8 p. 1779 - 1787
反应条件
hydrogen; palladium in methanol; water; acetic acid
参考文献
Gibian,H.; Schroeder,E.
Justus Liebigs Annalen der Chemie, 1961 , vol. 642, p. 145 - 162
反应条件
hydrogen; palladium on activated charcoal in acetic acid
参考文献
Harris,G.; MacWilliam,I.C.
Journal of the Chemical Society, 1961 , p. 2053 - 2057
反应条件
1: 1) Et3N, isobutyl chloroformate or pivaloyl chloride 2) Et3N / 1) CHCl3, -10 deg C 2) 0 deg C, 1 h, then 18-25 deg C, 16 h
2: 96 percent / HCOONH4 / Pd/C / ethanol / 1 h / H2/Pd was tested as well
View Scheme
参考文献
Kulikov, S. V.; Sokolova, N. Yu.; Samartsev, M. A.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, p. 1625 - 1631
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 8 p. 1779 - 1787
反应条件
2: DCC
3: aq. NaOH
4: H2 / Pd-C / acetic acid
View Scheme
参考文献
Harris,G.; MacWilliam,I.C.
Journal of the Chemical Society, 1961 , p. 2053 - 2057
反应条件
1: DCC
2: aq. NaOH
3: H2 / Pd-C / acetic acid
View Scheme
参考文献
Harris,G.; MacWilliam,I.C.
Journal of the Chemical Society, 1961 , p. 2053 - 2057
反应条件
1: NO2/HNO3, SO3/H2SO4
2: aq. NaOH
3: (i) Et3N, ClCO2Et, (ii) /BRN= 1953220/
4: H2 / Pd / methanol; acetic acid; H2O
View Scheme
参考文献
Gibian,H.; Schroeder,E.
Justus Liebigs Annalen der Chemie, 1961 , vol. 642, p. 145 - 162
反应条件
ammonium formate; palladium on activated charcoal in ethanol
2 h; H2/Pd was tested as well; Product distribution;
参考文献
Kulikov, S. V.; Sokolova, N. Yu.; Samartsev, M. A.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, p. 1625 - 1631
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 8 p. 1779 - 1787
反应条件
magnesium sulphate heptahydrate; recombinant L-amino acid ligase RizA; ATP disodium salt; tri-(hydroxymethyl)-methylamine in water
T=30°C; pH=8; 18 h; aq. buffer;
参考文献
Kino, Kuniki; Kotanaka, Yoichi; Arai, Toshinobu; Yagasaki, Makoto
Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 4 p. 901 - 907
