2-氯甲基-1,3-苯并恶唑合成路线 （共 18 条）
反应条件
in N,N-dimethyl-formamide T=90°C;
参考文献
Ilkun, Olesya T.; Archibald, Stephen J.; Barnes, Charles L.; Gerasimchuk, Nikolay; Biagioni, Richard; Silchenko, Svitlana; Gerasimchuk, Olga A.; Nemykin, Victor N.
Dalton Transactions, 2008 , # 42 p. 5715 - 5729
反应条件
ammonium hydroxide in tetrahydrofuran T=20 - 60°C; 22.5 h;
参考文献
Mutabilis
Patent: EP2141164 A1, 2010 ;
Location in patent: Page/Page column 38-39 ;
反应条件
1: isopentylnitrite, HCl / dioxane 2: NaN3 / dimethylformamide 3: AcOH / 12 h / 80 °C View Scheme
参考文献
Kristinsson,H.
Synthesis, 1979 , p. 102 - 103
反应条件
triethylamine in acetonitrile 20 h; Heating;
参考文献
Saari, Walfred S.; Wai, John S.; Fisher, Thorsten E.; Thomas, Craig M.; Hoffman, Jacob M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3792 - 3802
反应条件
Na2S*9H2O; tetrabutylammomium bromide in chloroform
KineticsMechanism; Reagent/catalystSolventTemperature;
参考文献
Yang, Zu-Shou; Zeng, Zuo-Xiang; Xue, Wei-Lan; Zhang, Ying
Journal of Chemical and Engineering Data, 2008 , vol. 53, # 11 p. 2692 - 2695
反应条件
sulfur; triethylamine in N,N-dimethyl-formamide
3 h;
参考文献
Thiel, W.; Mayer, R.
Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 2 p. 243 - 262
反应条件
1: 1.) S8, NEt3 / 1.) DMF, 2 h, 2.) 10 deg C
2: 55 percent / ethanol / 0.05 h / Heating
View Scheme
参考文献
Thiel, W.; Mayer, R.
Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 2 p. 243 - 262
反应条件
1: 1.) S8, NEt3 / 1.) DMF, 2 h, 2.) 10 deg C
2: 75 percent / ethanol / 0.05 h / Heating
View Scheme
参考文献
Thiel, W.; Mayer, R.
Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 2 p. 243 - 262
