2,5-二碘-1,3-二甲苯合成路线 （共 6 条）
反应条件
1: phenol With sodium hydride in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: With copper(l) chloride in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 3: 1,4-diiodo-2,6-dimethylbenzene Further stages;
参考文献
Angewandte Chemie - International Edition, , vol. 49, # 12 p. 2185 - 2189
反应条件
1: phenol With sodium hydride in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: With copper(l) chloride in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 3: 1,4-diiodo-2,6-dimethylbenzene Further stages;
参考文献
Angewandte Chemie - International Edition, , vol. 49, # 12 p. 2185 - 2189
反应条件
1: Diazotization;
2: iododediazotisation;
参考文献
Branchi, Barbara; Galli, Carlo; Gentili, Patrizia; Marinelli, Manuela; Mencarelli, Paolo
European Journal of Organic Chemistry, 2000 , # 14 p. 2663 - 2668
反应条件
1: 70 percent / I2; Ag2SO4
2: 75 percent
View Scheme
参考文献
Branchi, Barbara; Galli, Carlo; Gentili, Patrizia; Marinelli, Manuela; Mencarelli, Paolo
European Journal of Organic Chemistry, 2000 , # 14 p. 2663 - 2668
反应条件
potassium iodide; sodium nitrite
1) H2O, 0-5 deg C, 2a) H2O, 0-5 deg C, 1h, 2) reflux, 30 min; Yield given. Multistep reaction;
参考文献
Bryce, Martin R.; Davies, Stephen R.; Grainger, Andrew M.; Hellberg, Jonas; Hursthouse, Michael B.; et al.
Journal of Organic Chemistry, 1992 , vol. 57, # 6 p. 1690 - 1696
反应条件
(i) NaNO2, H2SO4, (ii) aq. KI; Multistep reaction;
参考文献
Suzuki,H. et al.
Bulletin of the Chemical Society of Japan, 1965 , vol. 38, p. 1590 - 1595
