2-[(Z)-2-戊烯基]环戊烯-1-酮合成路线 （共 38 条）
反应条件
1: 1.) p-toluenesulfonic acid, paraformaldehyde; 2.) BF3*Et2O / 1.) acetone, water, rt, 4 h; 2.) rt, 15 h
2: 90 percent / 1percent NaOH / diethyl ether; H2O / 72 h
View Scheme
参考文献
Rosini, Goffredo; Ballini, Roberto; Petrini, Marino; Sorrenti, Pietro
Tetrahedron, 1984 , vol. 40, # 19 p. 3809 - 3814
反应条件
1: 94 percent / lithium aluminium hydride / tetrahydrofuran / 0.33 h / 0 °C
2: 1.) p-toluenesulfonic acid, paraformaldehyde; 2.) BF3*Et2O / 1.) acetone, water, rt, 4 h; 2.) rt, 15 h
3: 90 percent / 1percent NaOH / diethyl ether; H2O / 72 h
View Scheme
参考文献
Rosini, Goffredo; Ballini, Roberto; Petrini, Marino; Sorrenti, Pietro
Tetrahedron, 1984 , vol. 40, # 19 p. 3809 - 3814
反应条件
1: 74 percent / SOCl2, pyridine / diethyl ether / 2 h / Ambient temperature
2: tetrahydrofuran / 2 h / -78 - 20 °C
3: 68 percent / oxalic acid / H2O / 3 h / Heating
4: 69 percent / NaOH / H2O; dioxane / 1.5 h / Heating
View Scheme
参考文献
Sato, Toshio; Kawara, Tatsuo; Sakata, Kazumi; Fujisawa, Tamotsu
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 2 p. 505 - 508
反应条件
1: 68 percent / oxalic acid / H2O / 3 h / Heating
2: 69 percent / NaOH / H2O; dioxane / 1.5 h / Heating
View Scheme
参考文献
Sato, Toshio; Kawara, Tatsuo; Sakata, Kazumi; Fujisawa, Tamotsu
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 2 p. 505 - 508
反应条件
1: 9.4 g / KOH, PEG-600 / diethyl ether / 1 h / Heating
2: 2.7 g / Br2 / methanol / 0.5 h
View Scheme
参考文献
Liu, Zhu-Jin; Rong, Guo-Bin
Synthetic Communications, 1986 , vol. 16, # 8 p. 871 - 876
反应条件
1: 9.4 g / KOH, PEG-600 / diethyl ether / 1 h / Heating
2: 2.7 g / Br2 / methanol / 0.5 h
View Scheme
参考文献
Liu, Zhu-Jin; Rong, Guo-Bin
Synthetic Communications, 1986 , vol. 16, # 8 p. 871 - 876
反应条件
1: 70 percent / PBr3, pyridine / 2 h / Ambient temperature
2: 57 percent / NaNO2 / dimethylformamide / 5 h / Ambient temperature
3: 64 percent / Al2O3 / diethyl ether / 7 h / Ambient temperature
4: 1.) MeONa, 2.) conc. H2SO4 / 1.) MeOh, 2.) -35 deg C, 10 min
5: 90 percent / NaOH / diethyl ether / 3 h
View Scheme
参考文献
Ballini, Roberto; Petrini, Marino; Marotta, Emanuela
Synthetic Communications, 1989 , vol. 19, # 3and4 p. 575 - 584
反应条件
1: 57 percent / NaNO2 / dimethylformamide / 5 h / Ambient temperature
2: 64 percent / Al2O3 / diethyl ether / 7 h / Ambient temperature
3: 1.) MeONa, 2.) conc. H2SO4 / 1.) MeOh, 2.) -35 deg C, 10 min
4: 90 percent / NaOH / diethyl ether / 3 h
View Scheme
参考文献
Ballini, Roberto; Petrini, Marino; Marotta, Emanuela
Synthetic Communications, 1989 , vol. 19, # 3and4 p. 575 - 584
反应条件
1: 64 percent / Al2O3 / diethyl ether / 7 h / Ambient temperature
2: 1.) MeONa, 2.) conc. H2SO4 / 1.) MeOh, 2.) -35 deg C, 10 min
3: 90 percent / NaOH / diethyl ether / 3 h
View Scheme
参考文献
Ballini, Roberto; Petrini, Marino; Marotta, Emanuela
Synthetic Communications, 1989 , vol. 19, # 3and4 p. 575 - 584
反应条件
1: 1.) MeONa, 2.) conc. H2SO4 / 1.) MeOh, 2.) -35 deg C, 10 min
2: 90 percent / NaOH / diethyl ether / 3 h
View Scheme
参考文献
Ballini, Roberto; Petrini, Marino; Marotta, Emanuela
Synthetic Communications, 1989 , vol. 19, # 3and4 p. 575 - 584
