6-甲氧基-4-甲基喹啉水合物合成路线 （共 33 条）
参考文献
Le Men
Bulletin de la Societe Chimique de France, 1950 , p. 599
参考文献
Le Men
Bulletin de la Societe Chimique de France, 1950 , p. 599
反应条件
selenium(IV) oxide in 1,4-dioxane; water T=85°C; Oxidation; 5 h;
参考文献
Friestad, Gregory K.; Ji, An; Korapala, Chandra Sekhar; Qin, Jun
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 11 p. 4039 - 4043
反应条件
1: 57 percent / mCPBA / CH2Cl2 / 16 h / Ambient temperature 2: 72 percent / 17 h / Ambient temperature 3: BBr3 / CH2Cl2 / 16 h / Ambient temperature View Scheme
参考文献
Unno, Ryoichi; Michishita, Hisashi; Inagaki, Hideaki; Suzuki, Yoko; Baba, Yutaka; Jomori, Takahito; Moku, Masatoshi; Nishikawa, Toshio; Isobe, Minoru
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 5 p. 903 - 919
参考文献
Clapp; Tipson
Journal of the American Chemical Society, 1946 , vol. 68, p. 1332
反应条件
1.1: m-CPBA / CH2Cl2 / 20 °C 1.2: Ac2O / 20 °C 1.3: 43 percent / K2CO3 / methanol 2.1: SOCl2 / CH2Cl2 / Heating 3.1: n-BuLi / tetrahydrofuran 4.1: 82 percent / NaH / tetrahydrofuran / 20 °C 5.1: 87 percent / AD-mix-α / 0 - 20 °C 6.1: MeC(OMe)3; PPTS / CH2Cl2 6.2: 88 percent / TMSCl; K2CO3 / methanol 7.1: DIBAL-H / toluene 8.1: DMF / 160 °C View Scheme
参考文献
Igarashi, Junji; Katsukawa, Masahiro; Wang, Yong-Gang; Acharya, Hukum P.; Kobayashi, Yuichi
Tetrahedron Letters, 2004 , vol. 45, # 19 p. 3783 - 3786
反应条件
1.1: m-CPBA / CH2Cl2 / 20 °C 1.2: Ac2O / 20 °C 1.3: 43 percent / K2CO3 / methanol 2.1: SOCl2 / CH2Cl2 / Heating 3.1: n-BuLi / tetrahydrofuran 4.1: 82 percent / NaH / tetrahydrofuran / 20 °C 5.1: 87 percent / AD-mix-α / 0 - 20 °C 6.1: MeC(OMe)3; PPTS / CH2Cl2 6.2: 88 percent / TMSCl; K2CO3 / methanol 7.1: DIBAL-H / toluene 8.1: DMF / 160 °C View Scheme
参考文献
Igarashi, Junji; Katsukawa, Masahiro; Wang, Yong-Gang; Acharya, Hukum P.; Kobayashi, Yuichi
Tetrahedron Letters, 2004 , vol. 45, # 19 p. 3783 - 3786
反应条件
1.1: m-CPBA / CH2Cl2 / 20 °C 1.2: Ac2O / 20 °C 1.3: 43 percent / K2CO3 / methanol 2.1: SOCl2 / CH2Cl2 / Heating 3.1: n-BuLi / tetrahydrofuran 4.1: 82 percent / NaH / tetrahydrofuran / 20 °C 5.1: 87 percent / AD-mix-α / 0 - 20 °C 6.1: MeC(OMe)3; PPTS / CH2Cl2 6.2: 88 percent / TMSCl; K2CO3 / methanol 7.1: DIBAL-H / toluene 8.1: DMF / 160 °C View Scheme
参考文献
Igarashi, Junji; Katsukawa, Masahiro; Wang, Yong-Gang; Acharya, Hukum P.; Kobayashi, Yuichi
Tetrahedron Letters, 2004 , vol. 45, # 19 p. 3783 - 3786
参考文献
Tipson; Walton
Journal of the American Chemical Society, 1948 , vol. 70, p. 892,894
反应条件
1: With 3-chloro-benzenecarboperoxoic acid in dichloromethane
T=20°C;
2: With acetic anhydride
T=20°C;
3: With potassium carbonate in methanol
Further stages.;
参考文献
Igarashi, Junji; Katsukawa, Masahiro; Wang, Yong-Gang; Acharya, Hukum P.; Kobayashi, Yuichi
Tetrahedron Letters, 2004 , vol. 45, # 19 p. 3783 - 3786
