2-苯基咪唑并[1,2-a]吡啶合成路线 （共 59 条）
反应条件
potassium hydroxide in ethanol 1 h; Heating;
参考文献
Katagiri, Nobuya; Kato, Tetsuzo; Niwa, Ryuji
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 407 - 412
反应条件
in hydrogenchloride; chloroform
参考文献
Eastman Kodak Company
Patent: US4396547 A1, 1983 ;
反应条件
1: 2-aminopyridine With potassium carbonate in 1,4-dioxane 0.75 h; 2: phenyl(phenylethynyl)iodonium trifluoroacetate in 1,4-dioxane T=20°C; DarknessInert atmosphere; regioselective reaction;
参考文献
Dixon, Luke I.; Carroll, Michael A.; Gregson, Thomas J.; Ellames, George J.; Harrington, Ross W.; Clegg, William
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 35 p. 5877 - 5884
反应条件
1: 2-aminopyridine With potassium carbonate in o-di-fluorobenzene 0.75 h; 2: phenyl(phenylethynyl)iodonium trifluoroacetate in o-di-fluorobenzene T=20°C; DarknessInert atmosphere; SolventReagent/catalystConcentration; Overall yield = 55 percent; regioselective reaction;
参考文献
Dixon, Luke I.; Carroll, Michael A.; Gregson, Thomas J.; Ellames, George J.; Harrington, Ross W.; Clegg, William
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 35 p. 5877 - 5884
反应条件
potassium carbonate in chloroform 2 h; Heating;
参考文献
Liu, Zhi; Chen, Zhen-Chu; Zheng, Qin-Guo
Synthetic Communications, 2004 , vol. 34, # 2 p. 361 - 367
反应条件
1: tetrahydrofuran / Ambient temperature 2: potassium carbonate / tetrahydrofuran / 72 h View Scheme
参考文献
Kovtunenko, Volodimir; Potikha, Lyudmila; Turov, Aleksandr
Synthetic Communications, 2004 , vol. 34, # 19 p. 3609 - 3613
反应条件
copper(l) iodide; lithium carbonate T=95°C; 2 h;
参考文献
Huang, Huawen; Ji, Xiaochen; Tang, Xiaodong; Zhang, Min; Li, Xianwei; Jiang, Huanfeng
Organic Letters, 2013 , vol. 15, # 24 p. 6254 - 6257
反应条件
sulfuric acid; zinc T=60°C; 1 h;
参考文献
Bal'on, Ya. G.; Shul'man, M. D.; Smirnov, V. A.; Yukhomenko, M. M.; Yukhomenko, M. A.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 7.2 p. 1352 - 1356
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 7 p. 1566 - 1571
反应条件
copper(l) iodide in N,N-dimethyl-formamide T=80°C; Michael Addition; 2 h; Reagent/catalyst;
参考文献
Santra, Sougata; Bagdi, Avik Kumar; Majee, Adinath; Hajra, Alakananda
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 6 p. 1065 - 1070
反应条件
1: 2-aminopyridine With potassium carbonate in o-di-fluorobenzene 0.75 h; 2: Ph-EBX in o-di-fluorobenzene T=20°C; DarknessInert atmosphereReflux; Overall yield = 54 percent; regioselective reaction;
参考文献
Dixon, Luke I.; Carroll, Michael A.; Gregson, Thomas J.; Ellames, George J.; Harrington, Ross W.; Clegg, William
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 35 p. 5877 - 5884
