2',3',5'-三乙酰尿苷合成路线 （共 45 条）
反应条件
3,3-dimethyldioxirane in ethanol; dichloromethane; acetone T=25°C;
参考文献
Crestini; Saladino; Bernini; Mincione
Tetrahedron Letters, 1993 , vol. 34, # 48 p. 7785 - 7788
反应条件
1: pyridine / 2 h / 80 °C 2: H2O / 1,2-dimethoxy-ethane / 9 h / 125 °C View Scheme
参考文献
Nowak, Ireneusz; Robins, Morris J.
Organic Letters, 2005 , vol. 7, # 22 p. 4903 - 4905
反应条件
1: 1.) triethylamine, 2-mesitylenesulfonyl chloride, 4-N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane, triethylamine / 1.) dichloromethane, 20 deg C, 1 h, 2.) dichloromethane, 20 deg C, 1 h 2: tetrabutylammonium fluoride / tetrahydrofuran / 0.08 h / 20 °C 3: 4-nitrobenzaldoxime, N,N,N',N'-tetramethylguanidine / dioxane; H2O / 0.05 h / 20 °C 4: pyridine / 1 h / 20 °C View Scheme
参考文献
Zhou, X.-X.; Welch, C.J.; Chattopadhyaya, J.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 806 - 816
反应条件
1: triethylamine / CH2Cl2 / 0.33 h / 20 °C 2: 1.) triethylamine, 2-mesitylenesulfonyl chloride, 4-N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane, triethylamine / 1.) dichloromethane, 20 deg C, 1 h, 2.) dichloromethane, 20 deg C, 1 h 3: tetrabutylammonium fluoride / tetrahydrofuran / 0.08 h / 20 °C 4: 4-nitrobenzaldoxime, N,N,N',N'-tetramethylguanidine / dioxane; H2O / 0.05 h / 20 °C 5: pyridine / 1 h / 20 °C View Scheme
参考文献
Zhou, X.-X.; Welch, C.J.; Chattopadhyaya, J.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 806 - 816
反应条件
ammonium cerium(IV) nitrate; silica gel in dichloromethane
参考文献
AbuSbeih, Khaled; Bleasdale, Christine; Golding, Bernard T.; Kitson, Sean L.
Tetrahedron Letters, 1992 , vol. 33, # 33 p. 4807 - 4810
反应条件
hydrogen bromide; acetic acid in acetonitrile T=55 - 60°C; 5 h;
参考文献
Shiragami; Ineyama; Uchida; Izawa
Nucleosides and Nucleotides, 1996 , vol. 15, # 1-3 p. 47 - 58
反应条件
iodine in tetrahydrofuran 0.166667 h; Ambient temperaturestability tested under various deprotective conditions;
参考文献
Takaku, Hiroshi; Imai, Kazuaki; Nagai, Masato
Chemistry Letters, 1988 , # 5 p. 857 - 860
反应条件
1: 4-nitrobenzaldoxime, N,N,N',N'-tetramethylguanidine / dioxane; H2O / 0.05 h / 20 °C 2: pyridine / 1 h / 20 °C View Scheme
参考文献
Zhou, X.-X.; Welch, C.J.; Chattopadhyaya, J.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 806 - 816
反应条件
1: 4-nitrobenzaldoxime, N,N,N',N'-tetramethylguanidine / dioxane; H2O / 0.05 h / 20 °C 2: pyridine / 1 h / 20 °C View Scheme
参考文献
Zhou, X.-X.; Welch, C.J.; Chattopadhyaya, J.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 806 - 816
反应条件
1: 4-nitrobenzaldoxime, N,N,N',N'-tetramethylguanidine / dioxane; H2O / 0.05 h / 20 °C 2: pyridine / 1 h / 20 °C View Scheme
参考文献
Zhou, X.-X.; Welch, C.J.; Chattopadhyaya, J.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 806 - 816
