4-甲氧基乙酰乙酸甲酯合成路线

32807-28-64-氯乙酰乙酸甲酯

41051-15-44-甲氧基乙酰乙酸甲酯

参考文献

Lonza Ltd.
Patent: US4564696 A1, 1986 ;

41051-15-44-甲氧基乙酰乙酸甲酯

参考文献

E. I. du Pont de Nemours and Company; Brookhaven Science Associates
Patent: US6462206 B1, 2002 ;

107-03-9丙硫醇+

141-97-9乙酰乙酸乙酯

41051-15-44-甲氧基乙酰乙酸甲酯

参考文献

Bayer Aktiengesellschaft
Patent: US4120956 A1, 1978 ;

38330-80-2丙二酸单甲酯钾盐+

31059-08-2

41051-15-44-甲氧基乙酰乙酸甲酯

参考文献

Allan, Kevin M.; Hong, Boram D.; Stoltz, Brian M.
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 23 p. 4960 - 4964

6290-49-9甲氧基乙酸甲酯+

96-32-2溴乙酸甲酯

41051-15-44-甲氧基乙酰乙酸甲酯

参考文献

Brehm; Levenson
Journal of the American Chemical Society, 1954 , vol. 76, p. 5389

17790-81-74-溴-3-氧代-丁酸甲酯+

124-41-4甲醇钠

41051-15-44-甲氧基乙酰乙酸甲酯

参考文献

Simoneau, Bruno; Brassard, Paul
Tetrahedron, 1986 , vol. 42, # 14 p. 3767 - 3774

67-56-1甲醇

41051-15-44-甲氧基乙酰乙酸甲酯

参考文献

Brehm; Levenson
Journal of the American Chemical Society, 1954 , vol. 76, p. 5389

41051-15-44-甲氧基乙酰乙酸甲酯

325685-59-44-氯-6-(甲氧基甲基)-2-苯基嘧啶

参考文献

Gardinier, Kevin M.; Khoury, Richard G.; Lehn, Jean-Marie
Chemistry - A European Journal, 2000 , vol. 6, # 22 p. 4124 - 4131

41051-15-44-甲氧基乙酰乙酸甲酯

3122-78-96-(甲氧基甲基)-4(1H)-嘧啶酮

参考文献

BRISTOL-MYERS SQUIBB COMPANY; COOK II, James H.; MCDONALD, Ivar, M.; KING, Dalton; OLSON, Richard, E.; WANG, Nenghui; IWUAGWU, Christiana, I.; ZUSI, Christopher, F.; MACOR, John, E.
Patent: WO2011/53292 A1, 2011 ;
Location in patent: Page/Page column 220 ;
WO 2011/053292 A1

41051-15-44-甲氧基乙酰乙酸甲酯+

6313-33-3甲脒盐酸盐

3122-78-96-(甲氧基甲基)-4(1H)-嘧啶酮

参考文献

Das, Jagabandhu; Padmanabha, Ramesh; Chen, Ping; Norris, Derek J.; Doweyko, Arthur M.P.; Barrish, Joel C.; Wityak, John; Lombardo, Louis J.; Lee, Francis Y.F.
Patent: US2004/54186 A1, 2004 ;
Location in patent: Page 127-128 ;
US 20040054186 A1