4-庚基-4'-氰基联苯合成路线 （共 19 条）
反应条件
acetic anhydride 2 h; Heating;
参考文献
Ruolene, Yu. I.; Adomenas, P. V.; Sirutkaitis, R. A.; Denis, G. I.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 1187 - 1191
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 6 p. 1305 - 1310
反应条件
in N,N-dimethyl-formamide 6 h; Heating;
参考文献
Dabrowski; Witkiewicz; Kenig
Molecular crystals and liquid crystals, 1980 , vol. 58, # 3-4 p. 251 - 259
反应条件
1: 1) hydrazine hydrate, 2) KOH / 1) diethylene glycol, 130 deg C, 1 h, 2) diethylene glycol, 130 deg C, 2 h, then 160 deg C, 3 h 2: 1) TiCl4, 2) hydroxylamine hydrochloride, pyridine / 1) CH2Cl2, 0 deg C, 30 min, 2) ethanol, reflux, 2 h 3: 83 percent / acetic anhydride / 2 h / Heating View Scheme
参考文献
Dabrowski; Witkiewicz; Kenig
Molecular crystals and liquid crystals, 1980 , vol. 58, # 3-4 p. 251 - 259
反应条件
1: 1) TiCl4, 2) hydroxylamine hydrochloride, pyridine / 1) CH2Cl2, 0 deg C, 30 min, 2) ethanol, reflux, 2 h 2: 83 percent / acetic anhydride / 2 h / Heating View Scheme
参考文献
Dabrowski; Witkiewicz; Kenig
Molecular crystals and liquid crystals, 1980 , vol. 58, # 3-4 p. 251 - 259
反应条件
1: AlCl3 / CH2Cl2 / 5 h / Ambient temperature 2: 1) hydrazine hydrate, 2) KOH / 1) diethylene glycol, 130 deg C, 1 h, 2) diethylene glycol, 130 deg C, 2 h, then 160 deg C, 3 h 3: 1) TiCl4, 2) hydroxylamine hydrochloride, pyridine / 1) CH2Cl2, 0 deg C, 30 min, 2) ethanol, reflux, 2 h 4: 83 percent / acetic anhydride / 2 h / Heating View Scheme
参考文献
Ruolene, Yu. I.; Adomenas, P. V.; Sirutkaitis, R. A.; Denis, G. I.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 1187 - 1191
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 6 p. 1305 - 1310
反应条件
1: AlCl3 / CH2Cl2 / 5 h / Ambient temperature 2: 1) hydrazine hydrate, 2) KOH / 1) diethylene glycol, 130 deg C, 1 h, 2) diethylene glycol, 130 deg C, 2 h, then 160 deg C, 3 h 3: 1) TiCl4, 2) hydroxylamine hydrochloride, pyridine / 1) CH2Cl2, 0 deg C, 30 min, 2) ethanol, reflux, 2 h 4: 83 percent / acetic anhydride / 2 h / Heating View Scheme
参考文献
Dabrowski; Witkiewicz; Kenig
Molecular crystals and liquid crystals, 1980 , vol. 58, # 3-4 p. 251 - 259
反应条件
sulfuric acid T=180°C; 3 h;
参考文献
Cheung, Julie; Field, Leslie D.; Sternhell, Sever
Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 7044 - 7046
反应条件
1: 85 percent / 6M H2SO4 / 3 h / 180 °C
2: 100 percent / thionyl chloride / 3.5 h / Heating
View Scheme
参考文献
Cheung, Julie; Field, Leslie D.; Sternhell, Sever
Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 7044 - 7046
反应条件
1: NaOH / ethane-1,2-diol
2: aq. H2SO4, aq. H3BO3
View Scheme
参考文献
Merck
Patent: FR2288732DE2450088 , 19761976 ;
Chem.Abstr., 1976 , vol. 85, # 46219
反应条件
1: NaOH / ethane-1,2-diol
2: aq. H2SO4, aq. H3BO3
View Scheme
参考文献
Merck
Patent: FR2288732DE2450088 , 19761976 ;
Chem.Abstr., 1976 , vol. 85, # 46219
