2-(2,4-二氧代嘧啶-1-基)乙酸合成路线 （共 7 条）
反应条件
in toluene stoichiometric amts. refluxed in toluene in vac.; recrystn. from toluene, elem. anal.;
参考文献
Kelloe, Eleonora; Vrabel, Viktor; Rattay, Vladimir; Sivy, Julius; Kozisek, Jozef
Acta Crystallographica, Section C: Crystal Structure Communications, 1992 , vol. 48, p. 51 - 53
反应条件
in water 1 h; Ambient temperature;
参考文献
Capraro, Hans-Georg; Lang, Marc; Schneider, Peter
Heterocycles, 1989 , vol. 28, # 2 p. 643 - 652
反应条件
1: With potassium hydroxide in water
1 h; Reflux;
2: With hydrogenchloride in water
T=4°C; pH=2;
参考文献
McCarthy, Orla; Musso-Buendia, Alex; Kaiser, Marcel; Brun, Reto; Ruiz-Perez, Luis M.; Johansson, Nils Gunnar; Pacanowska, Dolores Gonzalez; Gilbert, Ian H.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 2 p. 678 - 688
反应条件
formaldehyd; hydrogen bromide in acetic acid
Heating;
参考文献
Kumar, Subodh; Malik, Vaishalli; Kaur, Navneet; Kaur, Kuljit
Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8483 - 8487
反应条件
potassium hydroxide; chloroacetic acid
参考文献
Richardson-Merrell Inc.
Patent: US3956288 A1, 1976 ;
反应条件
sodium dithionite; triethylamine; methylenecarboxanilide; benzo[g]pteridine-based cyclen-zinc(II) in acetonitrile
Irradiation;
参考文献
Wiest, Olaf; Harrison, Christopher B.; Saettel, Nicolas J.; Cibulka, Radek; Sax, Mirjam; Koenig, Burkhard
Journal of Organic Chemistry, 2004 , vol. 69, # 24 p. 8183 - 8185
参考文献
Capraro, Hans-Georg; Lang, Marc; Schneider, Peter
Heterocycles, 1989 , vol. 28, # 2 p. 643 - 652
