(R)-(+)-3-羟基-5-氧代-1-环戊烯-1-庚酸甲酯合成路线 (共 23 条)
反应条件
acetic acid in tetrahydrofuran; water 24 h; Ambient temperature;
参考文献
Gill, Melvyn; Rickards, Rodney W.
Australian Journal of Chemistry, 1981 , vol. 34, # 5 p. 1063 - 1071
参考文献
Murcia, M. Carmen; De La Herran, Gabriela; Plumet, Joaquin; Csaky, Aurelio G.
Synlett, 2007 , # 10 p. 1553 - 1556
反应条件
anhydrous guanidine in methanol T=0°C; Substitution; Mitsunobu inversion; 0.25 h;
参考文献
Rodriguez, Ana; Nomen, Miguel; Spur, Bernd Werner; Godfroid, Jean-Jacques
European Journal of Organic Chemistry, 1999 , # 10 p. 2655 - 2662
反应条件
1: (microbiological transformation) 2: Et3N 3: (i) Al, (ii) AcOH View Scheme
参考文献
Sih; Heather; Sood; Price; Peruzzotti; Lee
Journal of the American Chemical Society, 1975 , vol. 97, # 4 p. 865 - 874
反应条件
1: Et3N 2: (i) Al, (ii) AcOH View Scheme
参考文献
Sih; Heather; Sood; Price; Peruzzotti; Lee
Journal of the American Chemical Society, 1975 , vol. 97, # 4 p. 865 - 874
反应条件
1: 46 percent / PPL 2: 98 percent / guanidine View Scheme
参考文献
Rodriguez, Ana R.; Spur, Bernd W.
Tetrahedron Letters, 2002 , vol. 43, # 26 p. 4575 - 4579
反应条件
1: Et3N / CH2Cl2 / -10 °C 2: guanidine / methanol / 0.25 h / 0 °C View Scheme
参考文献
Rodriguez, Ana; Nomen, Miguel; Spur, Bernd Werner; Godfroid, Jean-Jacques
European Journal of Organic Chemistry, 1999 , # 10 p. 2655 - 2662
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
Tsujiyama; Ono; Yoshino; Okamoto; Sato
Tetrahedron Letters, 1990 , vol. 31, # 31 p. 4481 - 4484
反应条件
1: aq. phosphate buffer; dioxane / 30 h / pH 8 / Heating 2: 46 percent / PPL 3: 98 percent / guanidine View Scheme
参考文献
Murcia, M. Carmen; De La Herran, Gabriela; Plumet, Joaquin; Csaky, Aurelio G.
Synlett, 2007 , # 10 p. 1553 - 1556
反应条件
1: aq. phosphate buffer; dioxane / 30 h / pH 8 / Heating 2: 46 percent / PPL 3: 98 percent / guanidine View Scheme
参考文献
Murcia, M. Carmen; De La Herran, Gabriela; Plumet, Joaquin; Csaky, Aurelio G.
Synlett, 2007 , # 10 p. 1553 - 1556