6,7-二甲氧基-1,2,3,4-四氢-1-异喹啉羧酸合成路线 （共 4 条）
反应条件
1: 10 palladium on activated charcoal; hydrogen / ethanol / 12 h / 750.08 Torr
2: water; lithium hydroxide hydrate / tetrahydrofuran / 0.75 h
View Scheme
参考文献
Koelzer, Michael; Weitzel, Kerstin; Goeringer, H. Ulrich; Thines, Eckhard; Opatz, Till
ChemMedChem, 2010 , vol. 5, # 9 p. 1456 - 1464
反应条件
water; lithium hydroxide hydrate in tetrahydrofuran
0.75 h;
参考文献
Koelzer, Michael; Weitzel, Kerstin; Goeringer, H. Ulrich; Thines, Eckhard; Opatz, Till
ChemMedChem, 2010 , vol. 5, # 9 p. 1456 - 1464
反应条件
1: trichlorophosphate / ethanol; toluene / 3 h / Reflux
2: 10 palladium on activated charcoal; hydrogen / ethanol / 12 h / 750.08 Torr
3: water; lithium hydroxide hydrate / tetrahydrofuran / 0.75 h
View Scheme
参考文献
Koelzer, Michael; Weitzel, Kerstin; Goeringer, H. Ulrich; Thines, Eckhard; Opatz, Till
ChemMedChem, 2010 , vol. 5, # 9 p. 1456 - 1464
反应条件
1: diethyl ether / 1.75 h / 0 - 25 °C
2: trichlorophosphate / ethanol; toluene / 3 h / Reflux
3: 10 palladium on activated charcoal; hydrogen / ethanol / 12 h / 750.08 Torr
4: water; lithium hydroxide hydrate / tetrahydrofuran / 0.75 h
View Scheme
参考文献
Koelzer, Michael; Weitzel, Kerstin; Goeringer, H. Ulrich; Thines, Eckhard; Opatz, Till
ChemMedChem, 2010 , vol. 5, # 9 p. 1456 - 1464
