7-甲基-3,4-二氢-2H-苯并[b]氧杂环庚三烯-5-酮合成路线 (共 13 条)
反应条件
1: 96 percent / NaOMe / ethanol; 1,2-dichloro-benzene / 150 °C
2: 71 percent / polyphosphoric acid / 110 °C
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参考文献
Rueeger, Heinrich; Gerspacher, Marc; Buehlmayer, Peter; Rigollier, Pascal; Yamaguchi, Yasuchika; Schmidlin, Tibur; Whitebread, Steven; Nuesslein-Hildesheim, Barbara; Nick, Hanspeter; Cricione, Leoluca
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 10 p. 2451 - 2457
反应条件
1: 62 percent / K2CO3; tetrabutylammonium bromide / benzene; H2O / 16 h / Heating
2: 80 percent / NaH / tetrahydrofuran / 80 h / 25 °C
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参考文献
Nikitin, Kirill V.; Andryukhova, Nonna P.
Canadian Journal of Chemistry, 2004 , vol. 82, # 5 p. 571 - 578
反应条件
1: 74 percent / 4percent ethanolic KOH
2: 2 N NaOH, 30percent H2O2 / ethanol / Heating
3: 51 percent / gl. acetic acid / ethanol / Heating
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参考文献
Tripathi, Ravish C.; Tandon, V. K.; Khanna, J. M.; Saxena, Anil K.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 37 - 41