9-(2-丙烯基)腺嘌呤合成路线 （共 13 条）
反应条件
sodium hydride in N,N-dimethyl-formamide
T=70°C; 2 h;
参考文献
Thibon, Jacques; Latxague, Laurent; Deleris, Gerard
Journal of Organic Chemistry, 1997 , vol. 62, # 14 p. 4635 - 4642
反应条件
potassium hydroxide; Aliquatreg; 336 in neat (no solvent)
3 h; Ambient temperature;
参考文献
Platzer, Nicole; Galons, Herve; Bensaid, Younes; Miocque, Marcel; Bram, Georges
Tetrahedron, 1987 , vol. 43, # 9 p. 2101 - 2108
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 17 h / 20 °C / |Inert atmosphere
2: ammonia / tert-butyl alcohol / 21 h / 120 °C
3: potassium carbonate / 7 h / 200 °C / |Microwave irradiation
4: allyl halide / |Alkaline conditions
View Scheme
参考文献
Kania, Jindrich; Gundersen, Lise-Lotte
European Journal of Organic Chemistry, 2013 , # 10 p. 2008 - 2019
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
T=25 - 30°C; 3 h;
参考文献
Chavakula, Ramadas; Mutyala, Narayanarao; Chennupati, Srinivasarao
Organic Preparations and Procedures International, 2013 , vol. 45, # 4 p. 336 - 340
反应条件
1: ammonia / tert-butyl alcohol / 21 h / 120 °C
2: potassium carbonate / 7 h / 200 °C / |Microwave irradiation
3: allyl halide / |Alkaline conditions
View Scheme
参考文献
Kania, Jindrich; Gundersen, Lise-Lotte
European Journal of Organic Chemistry, 2013 , # 10 p. 2008 - 2019
反应条件
1: Na, liq. NH3
2: 39 percent / K2CO3 / dimethylformamide / 16 h / Heating
View Scheme
参考文献
Holy
Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 12 p. 3134 - 3144
反应条件
1.1: sodium hydroxide / N,N-dimethyl-formamide / 25 - 30 °C
1.2: 15 h / 25 - 125 °C
2.1: pyridine / chloroform / 25 - 30 °C
2.2: 7 h / -5 - 30 °C
3.1: potassium tert-butylate / N,N-dimethyl-formamide / 3 h / 25 - 30 °C
View Scheme
参考文献
Chavakula, Ramadas; Mutyala, Narayanarao; Chennupati, Srinivasarao
Organic Preparations and Procedures International, 2013 , vol. 45, # 4 p. 336 - 340
反应条件
in toluene
168 h; Reflux;
参考文献
Thalassitis, Andreas; Hadjipavlou-Litina, Dimitra J.; Litinas, Konstantinos E.; Miltiadou, Panagiotis
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 22 p. 6433 - 6436
反应条件
1: potassium carbonate / 7 h / 200 °C / |Microwave irradiation
2: allyl halide / |Alkaline conditions
View Scheme
参考文献
Kania, Jindrich; Gundersen, Lise-Lotte
European Journal of Organic Chemistry, 2013 , # 10 p. 2008 - 2019
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Lysakowska, Magdalena; Balzarini, Jan; Piotrowska, Dorota G.
Archiv der Pharmazie, 2014 , vol. 347, # 5 p. 341 - 353
