6-(氨甲基)-6,11-二氢二苯并氮杂卓合成路线 （共 7 条）
反应条件
1: With aluminium hydride; lithium aluminium tetrahydride; sulfuric acid in tetrahydrofuran T=20°C; 2.5 h; 2: With water in tetrahydrofuran T=0°C;
参考文献
USV LIMITED
Patent: WO2009/63504 A2, 2009 ;
Location in patent: Page/Page column 24 ;
反应条件
lithium aluminium tetrahydride; sulfuric acid in tetrahydrofuran 2 h; below 40 deg C; Yield given;
参考文献
Walther; Daniel; Bechtel; Brandt
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 4 p. 440 - 446
反应条件
1: 70.2 percent / dimethylsulfoxide / 3 h / 90 °C 2: 1) 100percent sulfuric acid, lithium aluminium hydride / tetrahydrofuran / 2 h / below 40 deg C View Scheme
参考文献
Walther; Daniel; Bechtel; Brandt
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 4 p. 440 - 446
反应条件
1: 52.5 percent / ethanol; tetrahydrofuran / 14 h View Scheme
参考文献
Walther; Daniel; Bechtel; Brandt
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 4 p. 440 - 446
反应条件
in methanol T=35 - 40°C; 1.5 - 1.66667 h;
参考文献
USV LIMITED
Patent: WO2009/63504 A2, 2009 ;
Location in patent: Page/Page column 24 ;
反应条件
in tetrahydrofuran; ethanol T=20°C;
参考文献
USV LIMITED
Patent: WO2009/63504 A2, 2009 ;
Location in patent: Page/Page column 25 ;
反应条件
in tetrahydrofuran; methanol; ethanol
参考文献
Boehringer Ingelheim KG
Patent: US4313931 A1, 1982 ;
US 4313931 A
