2-氯-1-碘-4-硝基苯合成路线 （共 15 条）
反应条件
hydrogen in tetrahydrofuran; water T=120°C; P=37503.8 Torr; 12 h; chemoselective reaction;
参考文献
Jagadeesh, Rajenahally V.; Surkus, Annette-Enrica; Junge, Henrik; Pohl, Marga-Martina; Radnik, Joerg; Rabeah, Jabor; Huan, Heming; Schunemann, Volker; Brueckner, Angelika; Beller, Matthias
Science, 2013 , vol. 342, # 6162 p. 1073 - 1076
反应条件
1: 210 - 215 °C 2: N2H4*H2O View Scheme
参考文献
Pan; Fletcher
Journal of medicinal chemistry, 1965 , vol. 8, # 4 p. 491 - 497
反应条件
potassium fluoride; copper monoiodide in diethyl ether; ethyl acetate; N,N-dimethyl-formamide
参考文献
Wyeth
Patent: EP1137645 B1, 2004 ;
Location in patent: Page 32 ;
参考文献
Bloom, Jonathan D.; DiGrandi, Martin J.; Dushin, Russell G.; Curran, Kevin J.; Ross, Adma A.; Norton, Emily B.; Terefenko, Eugene; Jones, Thomas R.; Feld, Boris; Lang, Stanley A.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 17 p. 2929 - 2932
参考文献
Kapil,R.S.
Journal of Organic Chemistry, 1960 , vol. 25, p. 841
