5-氯-2,3-二苯基吡嗪合成路线 （共 19 条）
反应条件
1: Me3SiCl / 0.5 h / Heating 2: PCl5 / Heating View Scheme
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1952 , vol. 74, p. 1580,1582
反应条件
trichlorophosphate 0.333333 h; Heating;
参考文献
Watahiki, Hiroko; Tsutsui, Mayumi; Akita, Yasuo; Watanabe, Tokuhiro; Kurihara, Teruo
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 465 - 473
反应条件
1: 87 percent / ethanol / 1) room temp. 2) reflux, 0.5 h 2: 82 percent / Sulfur / 0.5 h / 140 °C 3: 73.4 percent / 90percent H2O2, maleic anhydride / CHCl3 / 2 h / Heating 4: 86 percent / POCl3 / 0.33 h / Heating View Scheme
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1952 , vol. 74, p. 1580,1582
反应条件
1: 73.4 percent / 90percent H2O2, maleic anhydride / CHCl3 / 2 h / Heating 2: 86 percent / POCl3 / 0.33 h / Heating View Scheme
参考文献
Landquist
Journal of the Chemical Society, 1956 , p. 1885
反应条件
1: 82 percent / Sulfur / 0.5 h / 140 °C 2: 73.4 percent / 90percent H2O2, maleic anhydride / CHCl3 / 2 h / Heating 3: 86 percent / POCl3 / 0.33 h / Heating View Scheme
参考文献
Watahiki, Hiroko; Tsutsui, Mayumi; Akita, Yasuo; Watanabe, Tokuhiro; Kurihara, Teruo
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 465 - 473
反应条件
phosphorus pentachloride Heating; Yield given;
参考文献
Sato, Nobuhiro; Narita, Nobuhiko
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 783 - 786
反应条件
1: 81 percent / NaN3 / dimethylformamide / 5 h / 150 °C 2: 92 percent / 220 °C 3: 91 percent / 10percent aq. KOH / methanol / 14 h / Ambient temperature View Scheme
参考文献
Watanabe, T.; Nishiyama, J.; Hirate, R.; Uehara, K.; Inoue, M.; et al.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1277 - 1281
反应条件
1: 83 percent / m-chloroperbenzoic acid (87percent) / 1,2-dichloro-ethane / 24 h / 65 °C 2: 92 percent / sodium / 12 h / Heating 3: 70 percent / trimethylsilyl azide, diethylcarbamoyl chloride / acetonitrile / Heating View Scheme
参考文献
Sato, Nobuhiro; Miwa, Naoko; Hirokawa, Noriko
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 7 p. 885 - 888
参考文献
Yamagami, Chisako; Araki, Kozue; Ohnishi, Kyoko; Hanasato, Kaoru; Inaba, Haruko; Aono, Masahiro; Ohta, Akihiro
Journal of Pharmaceutical Sciences, 1999 , vol. 88, # 12 p. 1299 - 1304
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium formate in N,N-dimethyl-formamide T=100°C; 2 h;
参考文献
Akita, Yasuo; Ohta, Akihiro
Heterocycles, 1981 , vol. 16, # 8 p. 1325 - 1328
