4-氨基-4-甲基二苯醚合成路线 （共 14 条）
反应条件
nickel; hydrazine hydrate in ethanol T=40°C;
参考文献
Hellwinkel, Dieter; Stahl, Heinz
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1993 , vol. 48, # 4 p. 521 - 538
反应条件
copper(l) iodide; potassium carbonate; trans-N,N'-dimethylcyclohexane-1,2-diamine in n-butyronitrile T=70°C; 24 h; Inert atmosphere;
参考文献
Maiti, Debabrata; Buchwald, Stephen L.
Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17423 - 17429
反应条件
copper(l) iodide; potassium carbonate; trans-N,N'-dimethylcyclohexane-1,2-diamine in n-butyronitrile T=80°C; 24 h; Inert atmosphere;
参考文献
Maiti, Debabrata; Buchwald, Stephen L.
Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17423 - 17429
反应条件
1: p-cresol; naphthalene / 230 °C 2: aq.-ethanolic hydrochloric acid; tin View Scheme
参考文献
Weber; Sowa
Journal of the American Chemical Society, 1938 , vol. 60, p. 94
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 16 h;
参考文献
Dey, Archan; Desiraju, Gautam R.
Chemical Communications, 2005 , # 19 p. 2486 - 2488
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 16 h;
参考文献
Dey, Archan; Desiraju, Gautam R.
Chemical Communications, 2005 , # 19 p. 2486 - 2488
反应条件
1: p-cresol; naphthalene / 230 °C 2: aq.-ethanolic hydrochloric acid; tin View Scheme
参考文献
Cook
Journal of the American Chemical Society, 1903 , vol. 25, p. 61
反应条件
2: hydrochloric acid / bei der elektrolytischen Reduktion View Scheme
参考文献
Hellwinkel, Dieter; Stahl, Heinz
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1993 , vol. 48, # 4 p. 521 - 538
反应条件
1: 54 percent / KOH, Cu / 160 °C 2: 83 percent / hydrazine hydrate, Raney nickel / ethanol / 40 °C View Scheme
参考文献
McClellan, William J.; Dai, Yujia; Abad-Zapatero, Cele; Albert, Daniel H.; Bouska, Jennifer J.; Glaser, Keith B.; Magoc, Terry J.; Marcotte, Patrick A.; Osterling, Donald J.; Stewart, Kent D.; Davidsen, Steven K.; Michaelides, Michael R.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5620 - 5624
反应条件
1: aluminum oxide; potassium fluoride; 18-crown-6 ether / acetonitrile / Reflux 2: iron; ammonium chloride / tetrahydrofuran; ethanol; water / 85 °C View Scheme
参考文献
McClellan, William J.; Dai, Yujia; Abad-Zapatero, Cele; Albert, Daniel H.; Bouska, Jennifer J.; Glaser, Keith B.; Magoc, Terry J.; Marcotte, Patrick A.; Osterling, Donald J.; Stewart, Kent D.; Davidsen, Steven K.; Michaelides, Michael R.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5620 - 5624
