(2,3-二氟苯基)甲硫醇合成路线 (共 2 条)
反应条件
1: With thiourea in ethanol
2.5 h; Heating / reflux;
2: With sodium hydroxide; water in water
T=20°C; Heating / reflux;
3: With hydrogenchloride; water in water
T=0°C; pH=6;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/70903 A2, 2005 ;
Location in patent: Page/Page column 24-25; 27 ;
WO 2005/070903 A2
反应条件
1: in ethanol
3 h; Heating / reflux;
2: With sodium hydroxide in ethanol; water
3 h; Heating / reflux;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/18435 A1, 2004 ;
Location in patent: Page 57 ;
WO 2004/018435 A1