1-(3-苯氧基丙基)哌嗪合成路线 （共 6 条）
反应条件
sodium iodide in butanone
参考文献
Serdex - Societe d'Etudes, de Recherches, de Diffusion et d'Exploitation
Patent: US4127661 A1, 1978 ;
反应条件
in toluene T=85°C; 3 h;
参考文献
Capuano, Ben; Crosby, Ian T.; Lloyd, Edward J.; Podloucka, Anna; Taylor, David A.
Australian Journal of Chemistry, 2008 , vol. 61, # 12 p. 930 - 940
反应条件
in 1,4-dioxane; chloroform
参考文献
Mitsui Toatsu Chemicals, Incorporated
Patent: US5332739 A1, 1994 ;
反应条件
trifluoroacetic acid in dichloromethane T=0°C; Inert atmosphere;
参考文献
Bio, Moses; Nkepang, Gregory; You, Youngjae
Chemical Communications, 2012 , vol. 48, # 52 p. 6517 - 6519
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 8 h / 20 °C 2: trifluoroacetic acid / dichloromethane / 0 °C / Inert atmosphere View Scheme
参考文献
Bio, Moses; Nkepang, Gregory; You, Youngjae
Chemical Communications, 2012 , vol. 48, # 52 p. 6517 - 6519
反应条件
1: potassium carbonate / acetone / 12 h / Reflux 2: potassium carbonate / N,N-dimethyl-formamide / 8 h / 20 °C 3: trifluoroacetic acid / dichloromethane / 0 °C / Inert atmosphere View Scheme
参考文献
Bio, Moses; Nkepang, Gregory; You, Youngjae
Chemical Communications, 2012 , vol. 48, # 52 p. 6517 - 6519
