2-(4-氯丁氧基)四氢吡喃合成路线 （共 19 条）
反应条件
ethylenediamine in dimethyl sulfoxide 2 h; Ambient temperature; Yield given;
参考文献
Ando; Vu; Yoshida; Takahashi
Agricultural and Biological Chemistry, 1982 , vol. 46, # 3 p. 717 - 722
反应条件
lithium amide hexamethylphosphoroamide, 1.) 1h, room temperature, 2.) 10 h, 27-30 deg C; Multistep reaction;
参考文献
Kovalev, B. G.; Matveeva, E. D.; Stan, V. V.; Vovk, G. A.; Yudin, L. G.; Kost, A. N.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 10 p. 1728 - 1733
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 10 p. 2032 - 2038
参考文献
Crisan
Annales de Chimie (Cachan, France), 1956 , vol. <13>1, p. 436,459
反应条件
1: 93 percent / NaH / dimethylformamide / Ambient temperature
2: 67 percent / NaHCO3 / dioxane; H2O / Irradiation
View Scheme
参考文献
Ogura, Katsuyuki; Itoh, Shigeyuki; Takahashi, Kazumasa; Iida, Hirotada
Tetrahedron Letters, 1986 , vol. 27, # 52 p. 6381 - 6384
反应条件
water
und anschliessend mit Toluol-4-sulfonsaeure in Aethanol;
参考文献
Spiegelberg; Doebel
Helvetica Chimica Acta, 1956 , vol. 39, p. 283,287
反应条件
magnesium; ethylene dibromide
1.) THF, -78 deg C, 30 min, 2.) room temperature, 15 h; Yield given. Multistep reaction;
参考文献
Carruthers, William; Cumming, S. Andrew
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 10 p. 2383 - 2386
反应条件
(i) LiNEt2, HMPT, benzene, (ii) K, HMPT, tBuOH, (iii) TsOH; Multistep reaction;
参考文献
Debal,A. et al.
Synthesis, 1976 , p. 391 - 393
反应条件
sodium iodide in acetone
Substitution; 24 h; Heating;
参考文献
Rumbero, Angel; Borreguero, Isabel; Sinisterra, Jose V.; Alcantara, Andres R.
Tetrahedron, 1999 , vol. 55, # 52 p. 14947 - 14960
反应条件
lithium amide
hexamethylphosphoroamide, 1.) 1h, room temperature, 2.) 10 h, 30 deg C; Multistep reaction;
参考文献
Kovalev, B. G.; Matveeva, E. D.; Stan, V. V.; Vovk, G. A.; Yudin, L. G.; Kost, A. N.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 10 p. 1728 - 1733
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 10 p. 2032 - 2038
