1: Mg / 1) ether; 2) -78 deg C, 5 min; 3) HCl 1:1 2: 88 percent / ethyl polyphosphate / 1 h / 30 °C View Scheme

1: NaOH/H2O / 1) EtOH, H2O, reflux, 12 h; 2) NaOH, reflux, 12 h; 3) HCl 1:1 2: 88 percent / ethyl polyphosphate / 1 h / 30 °C View Scheme

T=50 - 60°C; Destillieren des Reaktionsprodukts unter 12-15 mm Druck;

1: 97 percent / Br2 / CHCl3 / Ambient temperature 2: 97 percent / DBU / acetonitrile / 0.33 h / 40 - 45 °C 3: 1.) NaOH / 1.) DMPU, room temperature, 15 min, 2.) DMPU 4: 94 percent / NaH, DMPU / dimethylformamide / 2 h / 100 °C 5: 74 percent / aq. NaOH / methanol / Heating 6: 88 percent / tetrahydrofuran / 0.75 h / Ambient temperature 7: 1.) PPh3, Pd(OAc)2, aq. Na2CO3 / 1.) DME, room temperature, 1 h, 2.) DME, reflux 8: 99 percent / POCl3 / acetonitrile / 0.5 h / Heating View Scheme

1: 1.) TiCl4, 2.) Et3N / 1.) CHCl3, reflux, 1 h, 2.) benzene, reflux, 2 h 2: 19 percent / methanol / 15 h / Irradiation 3: 95 percent / Pb(OAc)4 / benzene / 2 h / 50 °C View Scheme

titanium tetrachloride in chloroform 1.) 0 deg C, 15 min, 2.) r.t., 24 h;