双(3,4-二甲氧基苯基)甲酮合成路线 （共 39 条）
反应条件
1: KOH; NaOH; activated silver / 220 °C
2: dimethyl sulfate
View Scheme
参考文献
Pearl
Journal of the American Chemical Society, 1954 , vol. 76, p. 3635
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere
1.2: 3 h / -60 °C / Inert atmosphere
2.1: AlCl3, aluminium chloride / dichloromethane / 0.25 h / 20 °C / Inert atmosphere
2.2: 16 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Kuhakarn, Chutima; Surapanich, Nakin; Kamtonwong, Siriporn; Pohmakotr, Manat; Reutrakul, Vichai
European Journal of Organic Chemistry, 2011 , # 29 p. 5911 - 5918
反应条件
1.1: n-butyllithium / tetrahydrofuran / 0.75 h / -78 °C / |Inert atmosphere
1.2: 4.33 h / -78 - 20 °C / |Inert atmosphere
2.1: dipyridinium dichromate / dichloromethane / 24 h / 0 - 15 °C / |Inert atmosphere
View Scheme
参考文献
Peng, Yu; Luo, Zhen-Biao; Zhang, Jian-Jian; Luo, Long; Wang, Ya-Wen
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 43 p. 7574 - 7586
反应条件
1.1: n-butyllithium / tetrahydrofuran / 0.75 h / -78 °C / |Inert atmosphere
1.2: 4.33 h / -78 - 20 °C / |Inert atmosphere
2.1: dipyridinium dichromate / dichloromethane / 24 h / 0 - 15 °C / |Inert atmosphere
View Scheme
参考文献
Peng, Yu; Luo, Zhen-Biao; Zhang, Jian-Jian; Luo, Long; Wang, Ya-Wen
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 43 p. 7574 - 7586
反应条件
1: aqueous H2SO4 / anschliessend mit wss. NaOH behandeln
2: Na2Cr2O7; acetic acid
View Scheme
参考文献
Werber
Annali di Chimica (Rome, Italy), 1959 , vol. 49, p. 1898,1912
反应条件
potassium carbonate in acetonitrile
参考文献
Qi, Qingkai; Liu, Yifei; Fang, Xiaofeng; Zhang, Yumo; Chen, Peng; Wang, Yi; Yang, Bing; Xu, Bin; Tian, Wenjing; Zhang, Sean Xiao-An
RSC Advances, 2013 , vol. 3, # 21 p. 7996 - 8002
参考文献
Vanzetti
Memorie della Reale Accademia d'Italia, Classe di Scienze Fisiche, Matematiche e Naturali, 1937 , vol. 8, p. 411,428
反应条件
1: carbon disulfide; phosphorus pentachloride
2: aluminium chloride
View Scheme
参考文献
Vanzetti
Gazzetta Chimica Italiana, 1927 , vol. 57, p. 169
Chem. Zentralbl., 1928 , vol. 99, # I p. 2824
反应条件
sodium dichromate; acetic acid
参考文献
Oliverio
Bollettino delle Sedute della Accademia Gioenia di Scienze Naturali in Catania, 1937 , vol. <3>, # 4 p. 33,35
反应条件
sodium dichromate; acetic acid
参考文献
Werber
Annali di Chimica (Rome, Italy), 1959 , vol. 49, p. 1898,1912
