2-甲基-4-甲氧基二苯胺合成路线 （共 9 条）
反应条件
potassium hydroxide; Pd0(tris(tert-butyl)phosphine)2; N-hexadecyl-N,N,N-trimethylammonium bromide in water; toluene T=90°C; 0.25 h;
参考文献
Appleton Papers Inc.
Patent: US2007/73086 A1, 2007 ;
Location in patent: Page/Page column 7 ;
反应条件
potassium phosphate; N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine; tris(dibenzylideneacetone)dipalladium (0) in toluene T=110°C; Buchwald-Hartwig amination; 8 h;
参考文献
Buchwald, Stephen L.; Mauger, Christelle; Mignani, Gerard; Scholz, Ulrich
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 1-2 p. 23 - 39
反应条件
caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; tris(dibenzylideneacetone)dipalladium (0) in toluene T=110°C; Buchwald-Hartwig amination;
参考文献
Buchwald, Stephen L.; Mauger, Christelle; Mignani, Gerard; Scholz, Ulrich
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 1-2 p. 23 - 39
反应条件
potassium phosphate; aniline; triphenylphosphine; tris(dibenzylideneacetone)dipalladium (0) T=184°C; Buchwald-Hartwig amination; 8 h;
参考文献
Buchwald, Stephen L.; Mauger, Christelle; Mignani, Gerard; Scholz, Ulrich
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 1-2 p. 23 - 39
反应条件
iodine; potassium carbonate
参考文献
Yamamoto Kagaku Gosei Kabushiki Kaisha
Patent: US4330473 A1, 1982 ;
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US4804783 A1, 1989 ;
反应条件
potassium hydroxide; iodine; potassium carbonate in toluene
参考文献
Ciba-Geigy Corporation
Patent: US5679856 A1, 1997 ;
参考文献
Sunagawa; Ichii
Yakugaku Zasshi, 1959 , vol. 79, p. 1409
Chem.Abstr., 1960 , p. 6729
反应条件
1: With sulfuric acid T=15 - 25°C; Condensation; 24 h; 2: With sodium hydroxide in toluene Cyclization; 1 h; Heating;
参考文献
Yanagita, Mitsuhiro; Aoki, Izuo; Tokita, Sumio
Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 11 p. 2757 - 2763
