N-Cbz-DL-丙氨酸合成路线 （共 26 条）
反应条件
citrate buffer; dl-cysteine hydrochloride; papain T=50°C; 24 h;
参考文献
Moriniere, J. L.; Danree, B.; Lemoine, J.; Guy, A.
Synthetic Communications, 1988 , vol. 18, # 4 p. 441 - 444
反应条件
citrate buffer; dl-cysteine hydrochloride; papain T=50°C; 24 h;
参考文献
Moriniere, J. L.; Danree, B.; Lemoine, J.; Guy, A.
Synthetic Communications, 1988 , vol. 18, # 4 p. 441 - 444
反应条件
citrate buffer; dl-cysteine hydrochloride; papain T=50°C; 24 h;
参考文献
Moriniere, Jean-Luc; Danree, Bernard; Guy, Alain
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 347 - 358
反应条件
4-methyl-morpholine; DMT*brucine tetrafluoroborate; (-)-Brucine in acetonitrile T=0 - 20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Kolesinska, Beata; Kaminski, Zbigniew J.
Organic Letters, 2009 , vol. 11, # 3 p. 765 - 768
反应条件
1: ethyl chloroformate; aq. ammonia; triethylamine / tetrahydrofuran / 0.5 h / 0 °C 2: phosphorus oxychloride; pyridine / 0 - 20 °C View Scheme
参考文献
Grzonka,Z.; Liberek,B.
Roczniki Chemii, 1971 , vol. 45, p. 967 - 980
反应条件
4-methyl-morpholine; N-(4,6-dimethoxy-1,3,5-triazin-2-yl)strychninium tetrafluoroborate; [3H]-Strychnine in chloroform T=0 - 20°C;
参考文献
Kolesinska, Beata; Kasperowicz, Katarzyna; Sochacki, Marek; Mazur, Adam; Jankowski, Stefan; Kaminski, Zbigniew J.
Tetrahedron Letters, 2010 , vol. 51, # 1 p. 20 - 22
反应条件
2-chloro-4,6-dimethoxy-[1,3,5]triazine; [3H]-Strychnine in tetrahydrofuran T=0 - 20°C;
参考文献
Kaminski; Kolesinska; Kaminska; Gora
Journal of Organic Chemistry, 2001 , vol. 66, # 19 p. 6276 - 6281
反应条件
resolved on CSP cellulose tris(3,5-dimethylphenylcarbamate) by chiral HPLC;
参考文献
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; ARMSTRONG, Daniel, W.; PING, Sun; BREITBACH, Zachary, S.; WANG, Chunlei
Patent: WO2010/148191 A2, 2010 ;
Location in patent: Page/Page column 45-49; 51 ;
反应条件
citrate buffer; dl-cysteine hydrochloride; papain T=50°C; 24 h;
参考文献
Moriniere, J. L.; Danree, B.; Lemoine, J.; Guy, A.
Synthetic Communications, 1988 , vol. 18, # 4 p. 441 - 444
反应条件
2-chloro-4,6-dimethoxy-[1,3,5]triazine; (-)-Brucine in tetrahydrofuran
T=0 - 20°C; Product distribution; Further Variations:Reagents;
参考文献
Kaminski; Kolesinska; Kaminska; Gora
Journal of Organic Chemistry, 2001 , vol. 66, # 19 p. 6276 - 6281
