6-羟基甲基-吡啶-2-羧酸乙酯合成路线 (共 12 条)
反应条件
thionyl chloride in dichloromethane
参考文献
Hall, Adrian; Billinton, Andy; Brown, Susan H.; Chowdhury, Anita; Clayton, Nicholas M.; Giblin, Gerard M.P.; Gibson, Mairi; Goldsmith, Paul A.; Hurst, David N.; Naylor, Alan; Peet, Caroline F.; Scoccitti, Tiziana; Wilson, Alexander W.; Winchester, Wendy
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 9 p. 2599 - 2603
反应条件
1: With phosphorus tribromide in dichloromethane
T=0°C; 2 h;
2: With sodium hydrogencarbonate in dichloromethane
参考文献
Labbe, Genevieve; Krismanich, Anthony P.; De Groot, Sarah; Rasmusson, Timothy; Shang, Muhong; Brown, Matthew D.R.; Dmitrienko, Gary I.; Guillemette, J. Guy
Journal of Inorganic Biochemistry, 2012 , vol. 112, p. 49 - 58