glucose dehydrogenase; D-Gulose; maltose binding protein-fused recombinant flavin reductase; recombinant tryptophan-7-halogenase; nicotinamide adenine dinucleotide; Adenine-flavine dinucleotide; sodium chloride in isopropyl alcohol T=25°C; pH=7.4; Enzymatic reaction; regioselective reaction;

lithium aluminium tetrahydride in tetrahydrofuran 18 h; Heating;

1: diethyl ether / 3 h / 25 °C 2: Et3N / 2 h / 78 °C 3: LiAlH4 / tetrahydrofuran / 2 h / 66 °C View Scheme

1: Et3N / 2 h / 78 °C 2: LiAlH4 / tetrahydrofuran / 2 h / 66 °C View Scheme

(i) TsOH, benzene, (ii) aq. NaOH, EtOH; Multistep reaction;