2-羟基-4-氨基苯甲酸甲酯合成路线 （共 46 条）
反应条件
1: pyridine 2: H2 / Pd/C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 5 p. 1749 - 1761
反应条件
lithium hydride 1.) THF, RT, 15 min, 2.) THF, 65 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Knoelker, Hans-Joachim; Bauermeister, Michael
Journal of the Indian Chemical Society, 1994 , vol. 71, # 6-8 p. 345 - 354
反应条件
1: acetic acid / 1 h 2: sodium hydroxide / N,N-dimethyl-formamide 3: N-chloro-succinimide / N,N-dimethyl-formamide View Scheme
参考文献
Letters in Drug Design and Discovery, , vol. 9, # 5 p. 489 - 493
反应条件
1: acetic acid / 1 h 2: sodium hydroxide / N,N-dimethyl-formamide 3: N-bromosuccinmide / N,N-dimethyl-formamide 4: sodium hydroxide / ethanol View Scheme
参考文献
Deng, Xin; Zhao, Xinxin; Han, Jing; Wang, Jingjie; Huang, Wenlong; Qian, Hai; Ge, Liang
Letters in Drug Design and Discovery, 2012 , vol. 9, # 5 p. 489 - 493
反应条件
1: 94 percent / ethanol / 3.5 h / 45 °C 2: 97 percent / potassium carbonate / acetone / 8 h / Heating View Scheme
参考文献
Deng, Xin; Zhao, Xinxin; Han, Jing; Wang, Jingjie; Huang, Wenlong; Qian, Hai; Ge, Liang
Letters in Drug Design and Discovery, 2012 , vol. 9, # 5 p. 489 - 493
反应条件
1: acetic acid / 1 h 2: sodium hydroxide / N,N-dimethyl-formamide 3: N-chloro-succinimide / N,N-dimethyl-formamide View Scheme
参考文献
Deng, Xin; Zhao, Xinxin; Han, Jing; Wang, Jingjie; Huang, Wenlong; Qian, Hai; Ge, Liang
Letters in Drug Design and Discovery, 2012 , vol. 9, # 5 p. 489 - 493
反应条件
1: acetic acid / 1 h 2: sodium hydroxide / N,N-dimethyl-formamide 3: N-bromosuccinmide / N,N-dimethyl-formamide View Scheme
参考文献
Deng, Xin; Zhao, Xinxin; Han, Jing; Wang, Jingjie; Huang, Wenlong; Qian, Hai; Ge, Liang
Letters in Drug Design and Discovery, 2012 , vol. 9, # 5 p. 489 - 493
反应条件
sodium hydrogencarbonate in water; ethyl acetate T=0 - 20°C; 2.25 h;
参考文献
SUVEN LIFE SCIENCES LIMITED; Nirogi, Ramakrishna; Mohammed, Abdul Rasheed; Yarlagadda, Suresh; Ravella, Srinivasa Rao; Shinde, Anil Karbhari; Kamphampati, Ramasastri; Roayapalley, Praveen Kumar; Jayarajan, Pradeep; Bhyrapuneni, Gopinadh; Patnala, Sriramachandra Murthy; Ravula, Jyothsna; Jasti, Venkateswarlu
Patent: US2014/187581 A1, 2014 ;
Location in patent: Page/Page column ;
反应条件
in ethanol T=45°C; 3.5 h;
参考文献
MacKenzie, A. Roderick; Moody, Christopher J.; Rees, Charles W.
Tetrahedron, 1986 , vol. 42, # 12 p. 3259 - 3268
反应条件
in water; acetic anhydride
参考文献
DAK-Laboratoriet
Patent: US4933330 A1, 1990 ;
