5-(4-氟苯基)-1,3,4-噁二唑-2(3H)-硫酮合成路线 （共 7 条）
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Charistos; Vagenas; Tzavellas; Tsoleridis; Rodios
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 6 p. 1593 - 1598
反应条件
hydrogenchloride in water T=0 - 5°C;
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
反应条件
1: sulfuric acid 2: hydrazine hydrate / methanol 3: potassium hydroxide / ethanol View Scheme
参考文献
Murty; Ramalingeswara Rao; Katiki, Mohana Rao; Nath, Lekshmi R.; Anto, Ruby John
Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 4980 - 4991
反应条件
1: hydrazine hydrate / methanol / 6 h / Heating 2: KOH / ethanol / 8 h / Heating View Scheme
参考文献
Deora, Girdhar Singh; Karthikeyan, Chandrabose; Moorthy, N. S. Hari Narayana; Rathore, Vandana; Rawat, Arun K.; Tamrakar, Akhilesh K.; Srivastava; Trivedi, Piyush
Medicinal Chemistry Research, 2013 , vol. 22, # 11 p. 5344 - 5348
反应条件
1: hydrazine hydrate / methanol 2: potassium hydroxide / ethanol View Scheme
参考文献
Li, Pei; Yin, Juan; Xu, Weiming; Wu, Jian; He, Ming; Hu, Deyu; Yang, Song; Song, Baoan
Chemical Biology and Drug Design, 2013 , vol. 82, # 5 p. 546 - 556
反应条件
1: triethylamine / dichloromethane / 0 °C 2: hydrazine hydrate / methanol / 5 h / |Reflux 3: potassium hydroxide / methanol / 20 °C / |Reflux 4: hydrogenchloride / water / 0 - 5 °C View Scheme
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
反应条件
1: potassium hydroxide / methanol / 20 °C / |Reflux 2: hydrogenchloride / water / 0 - 5 °C View Scheme
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
