1: With 4-methyl-morpholine in dichloromethane T=-15 - 20°C; 2: With hydrogen; palladium on activated charcoal in methanol P=4654.46 Torr; 24 h; Further stages.;

1: With 4-methyl-morpholine in dichloromethane T=-15 - 20°C; 2: With hydrogen; palladium on activated charcoal in methanol P=4654.46 Torr; 24 h; Further stages.;

1: 55.1 percent / triethylamine / dimethylformamide; tetrahydrofuran / 4 °C 2: hydrogen bromide / acetic acid 3: 78.9 percent / triethylamine / dimethylformamide / Ambient temperature 4: hydrogen bromide / acetic acid 5: 66.5 percent / pyridine, triethylamine / 4 °C View Scheme

sodium tetrahydroborate; water T=-15°C;

1: With 4-methyl-morpholine in dichloromethane T=-15 - 20°C; 2: With hydrogen; palladium on activated charcoal in methanol P=4654.46 Torr; 24 h; Further stages.;

1: With 4-methyl-morpholine in dichloromethane T=-15 - 20°C; 2: With hydrogen; palladium on activated charcoal in methanol P=4654.46 Torr; 24 h; Further stages.;