3-氯-N,2-二甲基苯胺合成路线 （共 4 条）
反应条件
1: With borane-THF in tetrahydrofuran T=-40 - 20°C; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 3: With sodium hydroxide in water; acetonitrile
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BIOLIPOX AB
Patent: WO2008/129288 A2, 2008 ;
Location in patent: Page/Page column 57 ;
WO 2008/129288 A2
反应条件
hydrogen; nickel in ethanol T=100°C; P=51714.8 Torr;
参考文献
Baron, Margaret L.; Martin, Lisandra L.; Rae, Ian D.; Simmonds, Peta M.; Woolcock, Mark L.
Australian Journal of Chemistry, 1990 , vol. 43, # 4 p. 741 - 747
反应条件
1: 70 percent / ethanol / 0.5 h / Heating 2: H2 / Raney nickel / ethanol / 100 °C / 51714.8 Torr View Scheme
参考文献
Zhou, Jun; He, Jianjun; Wang, Binjie; Yang, Weijun; Ren, Hongjun
Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 6868 - 6870
反应条件
lithium aluminium tetrahydride in diethyl ether Inert atmosphereReflux;
参考文献
Zhou, Jun; He, Jianjun; Wang, Binjie; Yang, Weijun; Ren, Hongjun
Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 6868 - 6870
