乙基4-羟基-7-甲基-3-喹啉羧酸酯合成路线 （共 9 条）
反应条件
sodium hydroxide in water 0.5 h; Reflux;
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
反应条件
1: sodium hydroxide / water / 0.5 h / |Reflux 2: diphenylether / 0.75 h / |Reflux View Scheme
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
反应条件
1: sodium hydroxide / water / 0.5 h / |Reflux 2: diphenylether / 0.75 h / |Reflux 3: trichlorophosphate / 1 h / 140 °C View Scheme
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
反应条件
in diphenylether
0.5 h; Heating;
参考文献
Singh, Ram; Geetanjali
Synthesis, 2005 , # 14 art. no. P04405SS, p. 2315 - 2320
参考文献
3M Innovative Properties Company
Patent: US6110929 A1, 2000 ;
反应条件
1: 85 percent / ethanol / 16 h / Heating
2: 81 percent / diphenyl ether / 0.5 h / Heating
View Scheme
参考文献
Singh, Ram; Geetanjali
Synthesis, 2005 , # 14 art. no. P04405SS, p. 2315 - 2320
反应条件
1: 85 percent / ethanol / 16 h / Heating
2: 81 percent / diphenyl ether / 0.5 h / Heating
View Scheme
参考文献
Singh, Ram; Geetanjali
Synthesis, 2005 , # 14 art. no. P04405SS, p. 2315 - 2320
反应条件
1: 0.75 h / 110 °C
2: diphenylether / 0.5 h / |Reflux
View Scheme
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
反应条件
trichlorophosphate in toluene
30 h; Heating; Yield given;
参考文献
Karolak-Wojciechowska, Janina; Lange, Jerzy; Ksiazek, Waldemar; Gniewosz, Malgorzata; Rump, Slawomir
Farmaco, 1998 , vol. 53, # 8-9 p. 579 - 585
