1-氯-3-甲氧基-2-丙醇合成路线 （共 16 条）
反应条件
dihydrogen peroxide; TS-1 in methanol; water; 1,2-dichloro-benzene T=25 - 40°C; 1 h; Product distribution / selectivity;
参考文献
DOW GLOBAL TECHNOLOGIES, INC.; CRAMPTON, Hannah, L.; CARLBERG, Philip, J.; WEST, David, H.; HOOK, Bruce, D.; FAN, William, W.; FORLIN, Anna
Patent: WO2011/17401 A1, 2011 ;
Location in patent: Page/Page column 27; 31; 33 ;
反应条件
ammonium cerium(IV) nitrate T=65°C; 0.5 h;
参考文献
Chapuzet, Jean-Marc; Beauchemin, Sophie; Daoust, Benoit; Lessard, Jean
Tetrahedron, 1996 , vol. 52, # 12 p. 4175 - 4180
反应条件
boron trifluoride diethyl etherate in dichloromethane T=25°C;
参考文献
Kose, Aytekin; Altundas, Ramazan; Secen, Hasan; Kara, Yunus
Helvetica Chimica Acta, 2013 , vol. 96, # 7 p. 1325 - 1330
反应条件
hydrogenchloride T=120 - 140°C;
参考文献
Malinowskii; Wwedenskii
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1957 , vol. 23, p. 626
Chem.Abstr., 1958 , p. 9959
反应条件
lithium aluminium tetrahydride; boron trichloride 1.) CH2Cl2, 10 min, 2.) Et2O, 30 min; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bonner, Trevor G.; Lewis, David; Rutter, Keith
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1807 - 1810
反应条件
tin(IV) chloride Rate constant;
参考文献
Drugov, M. V.; Barantsevich, E. N.; Smirnov P. A.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 6 p. 1052 - 1056
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 6 p. 1157 - 1162
反应条件
sodium hydroxide T=5°C;
参考文献
Dishong, Dennis M.; Diamond, Craig J.; Cinoman, Michael I.; Gokel, Geoge W.
Journal of the American Chemical Society, 1983 , vol. 105, # 3 p. 586 - 593
反应条件
sodium hexamethyldisilazane in tetrahydrofuran T=80°C; 19 h;
参考文献
Perry, Benjamin; Beevers, Rebekah; Bennett, Gavin; Buckley, George; Crabbe, Tom; Gowers, Lewis; James, Lynwen; Jenkins, Kerry; Lock, Chris; Sabin, Verity; Wright, Sara
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 19 p. 5299 - 5302
反应条件
sodium azide in water; dimethyl sulfoxide T=50 - 90°C; 8 h;
参考文献
3M Innovation Properties Company
Patent: US2011/230670 A1, 2011 ;
Location in patent: Page/Page column 6-7 ;
参考文献
Koelsch
Journal of the American Chemical Society, 1943 , vol. 65, p. 2458
